Framework synthesis to inform the ideation and design of a paper-based health information system (PHISICC) (Publications)
Register of Controlled Trials (CENTRAL), Embase, Epistemonikos, Medline, in-Process on the Ovid platform, OpenGrey, PDQ Evidence ("pretty darnd quick" Evidence), the World Health Organization (WHO) Global Health
Non-Markovian modelling highlights the importance of age structure on Covid-19 epidemiological dynamics (Publications)
study shows the flexibility and robustness of PDE formalism to capture national COVID-19 dynamics and opens perspectives to study medium or long-term scenarios involving immune waning or virus evolution.
Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden (Publications)
guiding ongoing COVID-19 control strategies. Methods: With an individual-based transmission model, OpenCOVID, we simulated three viral properties; infectivity, severity, and immune-evading ability, all
Epidemiology and Viral Evolution | Research at Swiss TPH (Page)
https://www.swisstph.ch/en/about/mpi/epidemiology-and-viral-evolution
insights into the ever-evolving 'dance' between viruses and humans. Pathoplexus Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering [...] looking at factors like reinfection, waning immunity, and immune pressure on viral epitopes. Using an open-source resource on Nextstrain, the research will facilitate real-time tracking of NP-EV evolution
Implementation of a Digital Clinical Decision Support System / ICRC Libya (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/implementation-of-a-digital-clinical-decision-support-system-/-icrc-libya
health outcomes had been proven in a large-scale scientific evaluation (Schmitz T, Beynon F et al. BMJ Open 2022; doi:10.1136/bmjopen-2021-055315). In 2021, ICRC decided to replicate the ALMANACH project for [...] Ministry of Health Development of the ICT code to transcribe the clinical content to be processed by an open-source software called Community Health Toolkit (CHT) Elaboration of training material and facilitation
KvarQ: Targeted and direct variant calling in FastQ reads of bacterial genomes (Page)
https://www.swisstph.ch/en/about/mpi/tuberculosis-ecology-and-evolution/kvarq-targeted-and-direct-variant-calling-in-fastq-reads-of-bacterial-genomes
ng (the latter adapted and modified from SpolPred). Software KvarQ is written in Python and C, is open-source and published under GNU GPLv3. Pre-compiled packages are available for Windows 7 or later,
Caregiving can be costly: a qualitative study of barriers and facilitators to conducting kangaroo mother care in a US tertiary hospital neonatal... (Publications)
mothers of preterm infants (N = 20) at a large academic medical center in Massachusetts. A series of open-ended interview questions were designed to elicit all aspects of mothers' experiences and to understand
Intensified therapy with inhaled corticosteroids and long-acting β2-agonists at the onset of upper respiratory tract Infection to prevent chronic... (Publications)
driven, double-blind, randomised, placebo-controlled study. At inclusion, patients were assigned to open-labelled low maintenance dose ICS/LABA. Each patient was randomised either to intensified dose ICS/LABA
Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year... (Publications)
HIV testing improved engagement in care and viral suppression 12 months after diagnosis. However, open questions remain regarding long-term outcomes and the risk of propagating drug resistance. METHODS:
Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study (Publications)
overtreatment of tuberculosis and to underdiagnosis of possible differential diagnoses. METHODS: This open-label, parallel-group, superiority randomized controlled trial is done in a rural and an urban center