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1. Synthesis and evaluation of beta-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis (Publications)

   Synthesis and evaluation of beta-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis

   Relevance:

   Several beta-carbolines including naturally occurring substances and their corresponding cationic derivatives were synthesized and evaluated for antimalarial (antiplasmodial) activity in vitro and in

2. Inhibition of <em>Plasmodium falciparum</em> fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids (Publications)

   Inhibition of <em>Plasmodium falciparum</em> fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids

   Relevance:

   After the discovery of a potent natural flavonoid glucoside as a potent inhibitor of FabI, a large flavonoid library was screened against three important enzymes (i.e., FabG, FabZ, and FabI) involved

3. Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with <em>Plasmodium falciparum</em> and... (Publications)

   Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> Malaria

   Relevance:

   Background. In malaria-endemic areas it is recommended that febrile children be tested for malaria by rapid diagnostic test (RDT) or blood slide (BS) and receive effective malaria treatment only if re

4. Mapping the densities of malaria vectors within a single village (Publications)

   Mapping the densities of malaria vectors within a single village

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5. Relationships between the outcome of <em>Plasmodium falciparum</em> infection and the intensity of transmission in Africa (Publications)

   Relationships between the outcome of <em>Plasmodium falciparum</em> infection and the intensity of transmission in Africa

   Relevance:

6. Health information given by Swiss travel agencies (Publications)

   Health information given by Swiss travel agencies

   Relevance:

   Background. Many of the 1 million Swiss traveling to tropical or subtropical countries book their trip through travel agencies every year. These agencies are thus an important source of information ab

7. Logistic regression and latent class models for estimating positivities in diagnostic assays with poor resolution (Publications)

   Logistic regression and latent class models for estimating positivities in diagnostic assays with poor resolution

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8. Antiprotozoal activities of epimeric aminobicycles (Publications)

   Antiprotozoal activities of epimeric aminobicycles

   Relevance:

   We synthesized several 4-aminobicyclo[2.2.2] octan-2-ols and 4-amino-2-azabicyclo[3.2.2]nonanes from epimerized 4-amino-bicyclo[2.2.2]octan-2-ones. The new compounds were tested for their activity aga

9. Acute hepatitis A in a young returning traveler from Kenya despite immunization before departure (Publications)

   Acute hepatitis A in a young returning traveler from Kenya despite immunization before departure

   Relevance:

   Aluminum-adsorbed hepatitis A vaccines are known to be highly efficient. We present here the case of a patient who was immunized against hepatitis A before leaving for Kenya and who contracted an acut

10. The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus <em>Trypanosoma cruzi</em> and <em>Leishmania donovani</em> (Publications)

    The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus <em>Trypanosoma cruzi</em> and <em>Leishmania donovani</em>

    Relevance:

    The in vitro activity of 20 dicationic molecules containing either diguanidino or reversed amidine cationic groups were evaluated versus Trypanosoma cruzi and Leishmania donovani. The most active comp