Aminoalkyl derivatives of guanidine diaromatic minor groove binders with antiprotozoal activity (Publications)
Considering the strong DNA minor-groove binding observed for our previous series of di-aromatic symmetric and asymmetric guanidinium and 2-aminoimidazolinium derivatives, we report now the synthesis o
Validation of a questionnaire to assess dietary habits among 5-13-year old school children of farmers and anthroposophic families (Publications)
Objective. To evaluate dietary habits among 5-13-year old school children of farmers, anthroposophic families and controls and to evaluate the validity of a food questionnaire as part of a lifestyle q
Comparing universal kriging and land-use regression for predicting concentrations of gaseous oxides of nitrogen (NOx) for the Multi-Ethnic Study of... (Publications)
BACKGROUND: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data
Reinfection with <em>Schistosoma haematobium</em> following school-based chemotherapy with praziquantel in four highly endemic villages in Côte... (Publications)
We present the comparative evaluation of school-based chemotherapy with praziquantel on Schistosoma haematobium reinfection patterns, 6, 12, 18 and 24 months after systematic treatment of schoolchildr
Impact of a national HIV voluntary counselling and testing (VCT) campaign on VCT in a rural hospital in Tanzania (Publications)
Summary Objective To evaluate the impact of a national HIV voluntary counselling and testing (VCT) campaign on presentation to HIV care in a rural population in Tanzania. Methods Retrospective analysi
Systems to support health technology assessment (HTA) in member states of the European union with limited institutionalization of HTA (Publications)
OBJECTIVES: The aim of this study was to support health technology assessment (HTA) capacity building in Member States of the European Union with limited experience or without institutionalized HTA. T
Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late stage central nervous system African... (Publications)
We report the discovery of novel boron-containing molecules, exemplified by N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl-2-trifluoromethylbenzam ide (AN3520) and 4-Fluoro-N-(1-hydroxy-1,3-dihydr
Bis(oxyphenylene)benzimidazoles: a novel class of anti-<em>Plasmodium falciparum</em> agents (Publications)
A small library of 26 2,2'-[alkane-alpha,omega-diylbis(oxyphenylene)]bis-1H-benzimidazoles has been prepared and evaluated against Giardia intestinalis, Entamoeba histolytica, Trypanosoma brucei rhode
Dog ownership enhances symptomatic responses to air pollution in children with asthma (Publications)
BACKGROUND: Experimental data suggest that asthma exacerbation by ambient air pollutants is enhanced by exposure to endotoxin and allergens; however, there is little supporting epidemiologic evidence.