Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea (Publications)
A Phase I safety and immunogenicity study with a three-component blood- stage malaria vaccine was conducted in adult male subjects living in an endemic area of Papua New Guinea. The preparations were
Using human rights to improve maternal and neonatal health: history, connections and a proposed practical approach (Publications)
We describe the historical development of how maternal and neonatal mortality in the developing world came to be seen as a public-health concern, a human rights concern, and ultimately as both, leadin
In vivo investigations of selected diamidine compounds against <em>Trypanosoma evansi</em> using a mouse model (Publications)
Surra is an animal pathogenic protozoan infection, caused by Trypanosoma evansi, that develops into a fatal wasting disease. Control measures rely on diagnosis and treatment. However, with the continu
A "one health" surveillance and control of brucellosis in developing countries: moving away from improvisation (Publications)
Although a "One Health" approach has been successfully implemented for emerging infectious zoonotic diseases with pandemic potential, we still lack a conceptual framework to address enzootic diseases
Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines (Publications)
In an effort to address potential cardiotoxicity liabilities identified with earlier frontrunner compounds, a number of new 3,5-diaryl-2-aminopyridine derivatives were synthesized. Several compounds e
Biochemical membrane lipidomics during <em>Drosophila</em> development (Publications)
Lipids play critical roles in energy homeostasis, membrane structure, and signaling. Using liquid chromatography and mass spectrometry, we provide a comprehensive semiquantification of lipids during t