Targeted and non-targeted analysis of membrane lipids using mass spectrometry (Publications)
Mass spectrometry has gained popularity amongst cell biologists in recent years as a complementary tool to probe the metabolism and biological functions of lipids. Indeed, the technology offers unprec
Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities (Publications)
A remarkable increase in antimalarial in vitro activity was achieved by integration of spiroadamantane motifs in 6-alkylidene 1,2,4-trioxanes 3a-h via diastereoselective photooxygenation of allylic al
The impact of obesity on mortality in UA/non-ST-segment elevation myocardial infarction (Publications)
AIMS: Obesity is associated with diabetes mellitus and advanced coronary artery disease (CAD). Once a non-ST-elevation acute coronary syndrome has occurred, the association between obesity and prognos
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described... (Publications)
The first phytochemical investigation of the recently discovered East African liana Ancistrocladus tanzaniensis is described, resulting in the isolation and structural elucidation of two new naphthyli
Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new... (Publications)
Traditionally it has taken years or decades for new public health interventions targeting diseases found in developing countries to be accessible to those most in need. One reason for the delay has be