Searched for malaria.

1. Stratification of malaria incidence in Papua New Guinea (2011–2019): contribution towards a sub-national control policy (Publications)

   Stratification of malaria incidence in Papua New Guinea (2011–2019): contribution towards a sub-national control policy

   Relevance:

   Malaria risk in Papua New Guinea (PNG) is highly heterogeneous, between and within geographical regions, which is operationally challenging for control. To enhance targeting of malaria interventions in [...] Incidence maps show a contrast in malaria risk between coastal and inland areas influenced by altitude. However, the risk is highly variable in low-lying areas. Malaria interventions should be guided by [...] in PNG, we investigated risk factors and stratified malaria incidence at the level...

2. Multisectoral approach to support use of insecticide-treated net for malaria prevention among mobile and migrant populations in Myanmar: a systematic... (Publications)

   Multisectoral approach to support use of insecticide-treated net for malaria prevention among mobile and migrant populations in Myanmar: a systematic review

   Relevance:

   BACKGROUND: Myanmar is a premalaria elimination country with artemisinin-resistant malaria. A strategy for transmission control is focused on vulnerable groups such as mobile and migrant populations (MMPs) [...] (MSA). METHODS: This narrative systematic review addressed MSAs targeted to MMPs in Myanmar for malaria prevention. We searched relevant studies in electronic databases and present the narrative findings

3. Study protocol of a cluster randomized controlled trial of strategies to increase antenatal iron and folic acid supplementation and malaria... (Publications)

   Study protocol of a cluster randomized controlled trial of strategies to increase antenatal iron and folic acid supplementation and malaria prophylaxis in rural south-central Côte d’Ivoire

   Relevance:

   post-partum anaemia and malaria infection. Anaemia will be assessed using HEMOCUE devices; malaria infections will be assessed using standard rapid diagnostic tests named CareStart Malaria Pf (HRP2) Ag RDT (Multi [...] of antenatal iron and folic acid supplementation (IFAS) and intermittent preventive treatment of malaria in pregnancy (IPTp) remains low in many countries. Evidence on the most effective ways to increase [...] cost, impact and relative cost-effectiveness of two complementary...

4. Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of <em>Plasmodium falciparum</em> malaria (Publications)

   Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of <em>Plasmodium falciparum</em> malaria

   Relevance:

   and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for malaria, despite this, there are [...] are no HDAC inhibitors in clinical trials for malaria treatment. This can be attributed to the poor pharmacokinetics, bioavailability and selectivity of the HDAC inhibitors. METHODS: A collection of HDAC [...] orally and subcutaneously. CONCLUSION: FNDR-20123 may be a suitable candidate for...

5. Targeting the hypnozoites: towards an in vitro system for malaria drug discovery (Publications)

   Targeting the hypnozoites: towards an in vitro system for malaria drug discovery

   Relevance:

6. Costing malaria interventions from pilots to elimination programmes (Publications)

   Costing malaria interventions from pilots to elimination programmes

   Relevance:

   Background:Malaria programmes in countries with low transmission levels require evidence to optimize deploy-ment of current and new tools to reach elimination with limited resources. Recent pilots of

7. Communities and clinical trials: a case study from the RTS,S malaria vaccine trials in eastern Africa (Publications)

   Communities and clinical trials: a case study from the RTS,S malaria vaccine trials in eastern Africa

   Relevance:

   resource scarcity can intensify existing inequities. Here we present a case study of a phase III malaria vaccine clinical trial. Through qualitative interviews with researchers and caregivers of pediatric

8. Incorporating genetic selection into individual-based models of malaria and other infectious diseases (Publications)

   Incorporating genetic selection into individual-based models of malaria and other infectious diseases

   Relevance:

   Introduction

9. Reduced human-biting preferences of the African malaria vectors <em>Anopheles arabiensis</em> and <em>Anopheles gambiae</em> in an urban context:... (Publications)

   Reduced human-biting preferences of the African malaria vectors <em>Anopheles arabiensis</em> and <em>Anopheles gambiae</em> in an urban context: controlled, competitive host-preference experiments in Tanzania

   Relevance:

   BACKGROUND

10. Comparative assessment of insecticide resistance phenotypes in two major malaria vectors, <em>Anopheles funestus</em> and <em>Anopheles... (Publications)

    Comparative assessment of insecticide resistance phenotypes in two major malaria vectors, <em>Anopheles funestus</em> and <em>Anopheles arabiensis</em> in south-eastern Tanzania

    Relevance:

    Long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS) have greatly reduced malaria transmission in sub-Saharan Africa, but are threatened by insecticide resistance. In south-eastern [...] rn Tanzania, pyrethroid-resistant Anopheles funestus are now implicated in > 80% of malaria infections, even in villages where the species occurs at lower densities than the other vector, Anopheles arabiensis [...] arabiensis. This study compared the insecticide resistance phenotypes...