<em>myo</em>-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in <em>Trypanosoma brucei</em> (Publications)
myo-Inositol is an essential precursor for the production of inositol phosphates and inositol phospholipids in all eukaryotes. Intracellular myo-inositol is generated by de novo synthesis from glucose
SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents (Publications)
There is an urgent need for the development of new drugs for the treatment of neglected tropical diseases such as human African trypanosomiasis, Chagas disease and leishmaniasis. Azasterols, have been