Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents (Publications)
A series of near-linear biphenyl benzimidazole diamidines 5a-h were synthesized from their respective diamidoximes (4a-h), through the bis-O-acetoxyamidoxime, followed by hydrogenation in glacial acet
Association of daily physical activity volume and intensity with COPD severity (Publications)
PURPOSE: The purpose of this study was to assess whether daily walking activity is indicative of disease severity in patients with COPD. METHODS: Daily activity was measured by accelerometry in 107 CO
Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study (Publications)
BACKGROUND: The impact of outdoor air pollution on infant mortality has not been quantified. METHODS: Based on exposure-response functions from a U.S. cohort study, we assessed the attributable risk o
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents (Publications)
A series of analogues of the naturally occurring antibiotic thiolactomycin (TLM) have been synthesised and evaluated for their ability to inhibit the growth of the malaria parasite, Plasmodium falcipa
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents (Publications)
A series of phenyl-2,2'-bichalcophene diamidines 1a-h were synthesized from the corresponding dinitriles either via a direct reaction with LiN(TMS)(2), followed by deprotection with ethanolic HCl or t
Airbone particle number profiles, particle mass distributions and particle - bound PAH concentrations within the city environment of Basel: an... (Publications)
A project aimed at assessing a variety of particulate indicators was carried out at three locations in the city of Basel within the scope of the Basel Air Quality Risk Assessment Project (BRISKA). Siz
Treatment of breast cancer in the elderly: a prospective, population-based Swiss study (Publications)
Objectives: The primary objective of this population-based study is to describe the patterns of care of elderly patients with breast cancer (BC), and evaluate potential causative factors for the decre
Risks and benefits of optimised medical and revascularisation therapy in elderly patients with angina--on-treatment analysis of the TIME trial (Publications)
AIM: To assess treatment effects of optimised medical therapy and PCI or CABG surgery on one-year outcome in patients 75 years old with chronic angina. METHODS AND RESULTS: On-treatment analysis of th