Publications

Awor P, Coppée R, Khim N, Rondepierre L, Roesch C, Khean C, Kul C, Eam R, Lorn T, Athieno P, Kimera J, Balikagala B, Odongo-Aginya E.I, Anywar D.A, Mita T, Clain J, Ringwald P, Signorell A, Lengeler C, Burri C, Ariey F, Hetzel M.W, Witkowski B. Indigenous emergence and spread of kelch13 C469Y artemisinin-resistant Plasmodium falciparum in Uganda. Antimicrob Agents Chemother. 2024;68(8):e0165923. DOI: 10.1128/aac.01659-23

Giduthuri J.G, Timbi D, Kualawi M, Are C, Muri M, Philemon G, Hetzel M, Pomat W. Papua New Guinea malaria indicator survey 2022-2023: final report on malaria prevention, infection prevalence, and treatment-seeking. Goroka: Papua New Guinea Institute of Medical Research, 2024. DOI: 10.5281/zenodo.10630064

Holzschuh A, Lerch A, Fakih B.S, Aliy S.M, Ali M.H, Ali M.A, Bruzzese D.J, Yukich J, Hetzel M.W, Koepfli C. Using a mobile nanopore sequencing lab for end-to-end genomic surveillance of Plasmodium falciparum: a feasibility study. PLOS Glob Public Health. 2024;4(2):e0002743. DOI: 10.1371/journal.pgph.0002743

Brunner N.C, Karim A, Athieno P, Kimera J, Tumukunde G, Angiro I, Signorell A, Delvento G, Lee T.T, Lambiris M, Ogwal A, Nakiganda J, Mpanga F, Kagwire F, Amutuhaire M, Burri C, Lengeler C, Awor P, Hetzel M.W. Starting at the community: treatment-seeking pathways of children with suspected severe malaria in Uganda. PLOS Glob Public Health. 2023;3(7):e0001949. DOI: 10.1371/journal.pgph.0001949

Das A.M, Hetzel M.W, Yukich J.O, Stuck L, Fakih B.S, Al-mafazy A.H, Ali A, Chitnis N. Modelling the impact of interventions on imported, introduced and indigenous malaria infections in Zanzibar, Tanzania. Nat Commun. 2023;14:2750. DOI: 10.1038/s41467-023-38379-8

Fakih B.S, Holzschuh A, Ross A, Stuck L, Abdul R, Al-mafazy A.H, Irema I, Mbena A, Thawer S.G, Shija S.J, Aliy S.M, Ali A, Fink G, Yukich J, Hetzel M.W. Risk of imported malaria infections in Zanzibar: a cross-sectional study. Infect Dis Poverty. 2023;12:80. DOI: 10.1186/s40249-023-01129-5

Golumbeanu M, Edi C.A.V, Hetzel M.W, Koepfli C, Nsanzabana C. Bridging the gap from molecular surveillance to programmatic decisions for malaria control and elimination. Am J Trop Med Hyg. 2023(in press). DOI: 10.4269/ajtmh.22-0749

Hetzel M.W, Awor P, Tshefu A, Omoluabi E, Burri C, Signorell A, Lambiris M.J, Visser T, Cohen J.M, Buj V, Lengeler C. Pre-referral rectal artesunate: no cure for unhealthy systems. Lancet Infect Dis. 2023;23(6):e213-e217. DOI: 10.1016/S1473-3099(22)00762-9

Hetzel M.W, Okitawutshu J, Tshefu A, Omoluabi E, Awor P, Signorell A, Kwiatkowski M, Lambiris M.J, Visser T, Cohen J.M, Buj V, Burri C, Lengeler C. Pre-referral rectal artesunate is no "magic bullet" in weak health systems. BMC Med. 2023;21:119. DOI: 10.1186/s12916-023-02777-y

Holzschuh A, Lerch A, Gerlovina I, Fakih B.S, Al-mafazy A.H, Reaves E.J, Ali A, Abbas F, Ali M.H, Ali M.A, Hetzel M.W, Yukich J, Koepfli C. Multiplexed ddPCR-amplicon sequencing reveals isolated Plasmodium falciparum populations amenable to local elimination in Zanzibar, Tanzania. Nat Commun. 2023;14:3699. DOI: 10.1038/s41467-023-39417-1

Lambiris M.J, Venga G.N, Ssempala R, Balogun V, Galactionova K, Musiitwa M, Kagwire F, Olosunde O, Emedo E, Luketa S, Sangare M, Buj V, Delvento G, Tshefu A, Okitawutshu J, Omoluabi E, Awor P, Signorell A, Hetzel M.W, Lee T.T, Brunner N.C, Cereghetti N, Visser T, Napier H.G, Burri C, Lengeler C. Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and constraints. Lancet Glob Health. 2023;11(2):e256-e264. DOI: 10.1016/S2214-109X(22)00507-1

Mäser P, Bernhard S, Brun R, Burri C, Gagneux S, Hetzel M.W, Kaiser M, Lengeler C, Pluschke G, Reus E, Rottmann M, Utzinger J, Warryn L, Wittlin S, Keiser J. Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases. Chimia (Aarau). 2023;77(9):593-606. DOI: 10.2533/chimia.2023.593

Okitawutshu J, Tshefu A, Kalenga J.C, Delvento G, Burri C, Hetzel M.W, Lengeler C, Signorell A. Assessing caregivers' perceptions of treatment-seeking for suspected severe malaria in the Democratic Republic of the Congo. Malar J. 2023;22:308. DOI: 10.1186/s12936-023-04737-6

Signorell A, Awor P, Okitawutshu J, Tshefu A, Omoluabi E, Hetzel M.W, Athieno P, Kimera J, Tumukunde G, Angiro I, Kalenga J.C, Akano B.K, Ayodeji K, Okon C, Yusuf O, Delvento G, Lee T.T, Brunner N.C, Lambiris M.J, Okuma J, Cereghetti N, Buj V, Visser T, Napier H.G, Lengeler C, Burri C. Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: an operational study. PLoS Med. 2023;20(2):e1004189. DOI: 10.1371/journal.pmed.1004189

Awor P, Kimera J, Athieno P, Tumukunde G, Okitawutshu J, Tshefu A, Omoluabi E, Signorell A, Brunner N, Kalenga J.C, Akano B, Ayodeji K, Okon C, Yusuf O, Delvento G, Lee T, Burri C, Lengeler C, Hetzel M.W. Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda. Malar J. 2022;21:322. DOI: 10.1186/s12936-022-04348-7

Awor P, Kimera J, Brunner N.C, Athieno P, Tumukunde G, Angiro I, Signorell A, Delvento G, Lee T, Amutuhaire M, Opigo J, Kaggwa F.M, Kagwire F, Nakiganda J, Burri C, Lengeler C, Hetzel M.W. Care seeking and treatment of febrile children with and without danger signs of severe disease in northern Uganda: results from three household surveys (2018-2020). Am J Trop Med Hyg. 2022;107(4):934–938. DOI: 10.4269/ajtmh.21-1132

Brunner N.C, Omoluabi E, Awor P, Okitawutshu J, Tshefu Kitoto A, Signorell A, Akano B, Ayodeji K, Okon C, Yusuf O, Athieno P, Kimera J, Tumukunde G, Angiro I, Kalenga J.C, Delvento G, Lee T.T, Lambiris M.J, Ross A, Cereghetti N, Visser T, Napier H.G, Buj V, Burri C, Lengeler C, Hetzel M.W. Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda. BMJ Glob Health. 2022;7(5):e008346. DOI: 10.1136/bmjgh-2021-008346

Cleary E, Hetzel M.W, Clements A.C.A. A review of malaria epidemiology and control in Papua New Guinea 1900 to 2021: progress made and future directions. Front Epidemiol. 2022;2:980795. DOI: 10.3389/fepid.2022.980795

Das A.M, Hetzel M.W, Yukich J.O, Stuck L, Fakih B.S, Al-mafazy A.H, Ali A, Chitnis N. The impact of reactive case detection on malaria transmission in Zanzibar in the presence of human mobility. Epidemics. 2022;41:100639. DOI: 10.1016/j.epidem.2022.100639

Giduthuri J.G, Kualawi M, Muri M, Are C, Goi P, Minn Oo M, Hetzel M.W, Pomat W. Papua New Guinea national health facility survey 2021: availability and quality of malaria case management. Goroka: Papua New Guinea Institute of Medical Research, 2022

Hetzel M.W, Okitawutshu J, Tshefu A, Omoluabi E, Awor P, Signorell A, Brunner N.C, Kalenga J.C, Akano B.K, Ayodeji K, Okon C, Yusuf O, Athieno P, Kimera J, Tumukunde G, Angiro I, Delvento G, Lee T.T, Lambiris M.J, Kwiatkowski M, Cereghetti N, Visser T, Napier H.G, Cohen J.M, Buj V, Burri C, Lengeler C. Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study. BMC Med. 2022;20:343. DOI: 10.1186/s12916-022-02541-8

Keven J.B, Katusele M, Vinit R, Rodríguez-Rodríguez D, Hetzel M.W, Robinson L.J, Laman M, Karl S, Walker E.D. Vector composition, abundance, biting patterns and malaria transmission intensity in Madang, Papua New Guinea: assessment after 7 years of an LLIN-based malaria control programme. Malar J. 2022;21:7. DOI: 10.1186/s12936-021-04030-4

Lengeler C, Burri C, Awor P, Athieno P, Kimera J, Tumukunde G, Angiro I, Tshefu A, Okitawutshu J, Kalenga J.-C, Omoluabi E, Akano B, Ayodeji K, Okon C, Yusuf O, Brunner N.C, Delvento G, Lee T, Lambiris M.J, Visser T, Napier H.G, Cohen J.M, Buj V, Signorell A, Hetzel Manuel W, Caramal Consortium. Community access to rectal artesunate for malaria (CARAMAL): a large-scale observational implementation study in the Democratic Republic of the Congo, Nigeria and Uganda. PLoS Glob Public Health. 2022;2(9):e0000464. DOI: 10.1371/journal.pgph.0000464

Namango I.H, Marshall C, Saddler A, Ross A, Kaftan D, Tenywa F, Makungwa N, Odufuwa O.G, Ligema G, Ngonyani H, Matanila I, Bharmal J, Moore J, Moore S.J, Hetzel M.W. The Centres for Disease Control light trap (CDC-LT) and the human decoy trap (HDT) compared to the human landing catch (HLC) for measuring Anopheles biting in rural Tanzania. Malar J. 2022;21:181. DOI: 10.1186/s12936-022-04192-9

Naung M.T, Martin E, Munro J, Mehra S, Guy A.J, Laman M, Harrison G.L.A, Tavul L, Hetzel M, Kwiatkowski D, Mueller I, Bahlo M, Barry A.E. Global diversity and balancing selection of 23 leading Plasmodium falciparum candidate vaccine antigens. PLoS Comput Biol. 2022;18(2):e1009801. DOI: 10.1371/journal.pcbi.1009801

Okitawutshu J, Signorell A, Kalenga J.C, Mukomena E, Delvento G, Burri C, Mwaluke F, Buj V, Sangare M, Luketa S, Brunner N, Lee T, Hetzel M, Lengeler C, Tshefu A. Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo. Malar J. 2022;21:274. DOI: 10.1186/s12936-022-04296-2

Seidahmed O, Jamea S, Kurumop S, Timbi D, Makita L, Ahmed M, Freeman T, Pomat W, Hetzel M.W. Stratification of malaria incidence in Papua New Guinea (2011–2019): contribution towards a sub-national control policy. PLoS Glob Public Health. 2022;2(11):e0000747. DOI: 10.1371/journal.pgph.0000747

Vera-Arias C.A, Holzschuh A, Oduma C.O, Badu K, Abdul-Hakim M, Yukich J, Hetzel M.W, Fakih B.S, Ali A, Ferreira M.U, Ladeia-Andrade S, Sáenz F.E, Afrane Y, Zemene E, Yewhalaw D, Kazura J.W, Yan G, Koepfli C. High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy. eLife. 2022;11:e72083. DOI: 10.7554/eLife.72083

Awor P, Khim N, Coppée R, Rondepierre L, Roesch C, Khean C, Kul C, Eam R, Lorn T, Athieno P, Kimera J, Clain J, Ringwald P, Signorell A, Lengeler C, Burri C, Ariey F, Hetzel M.W, Witkowski B. Clonal expansion of artemisinin-resistant Plasmodium falciparum in Uganda is associated with substandard treatment practices. Lancet. 2021(in press). DOI: 10.2139/ssrn.3974542

Brunner N.C, Awor P, Hetzel M.W. Definitions of severity in treatment seeking studies of febrile illness in children in low and middle income countries: a scoping review. Int J Public Health. 2021;66:634000. DOI: 10.3389/ijph.2021.634000

Cleary E, Hetzel M.W, Siba P, Lau C.L, Clements A.C.A. Spatial prediction of malaria prevalence in Papua New Guinea: a comparison of Bayesian decision network and multivariate regression modelling approaches for improved accuracy in prevalence prediction. Malar J. 2021;20:269. DOI: 10.1186/s12936-021-03804-0

Cleary E, Hetzel M.W, Siba P.M, Lau C.L, Clements A.C.A. Correction to: Spatial prediction of malaria prevalence in Papua New Guinea: a comparison of Bayesian decision network and multivariate regression modelling approaches for improved accuracy in prevalence prediction. Malar J. 2021;20:318. DOI: 10.1186/s12936-021-03838-4

Gul D, Rodríguez-Rodríguez D, Nate E, Auwan A, Salib M, Lorry L, Keven J.B, Katusele M, Rosado J, Hofmann N, Ome-Kaius M, Koepfli C, Felger I, Kazura J.W, Hetzel M.W, Mueller I, Karl S, Clements A.C.A, Fowkes F.J.I, Laman M, Robinson L.J. Investigating differences in village-level heterogeneity of malaria infection and household risk factors in Papua New Guinea. Sci Rep. 2021;11:16540. DOI: 10.1038/s41598-021-95959-8

Keven J.B, Katusele M, Vinit R, Rodríguez-Rodríguez D, Hetzel M.W, Robinson L.J, Laman M, Karl S, Foran D.R, Walker E.D. Nonrandom selection and multiple blood feeding of human hosts by Anopheles vectors: implications for malaria transmission in Papua New Guinea. Am J Trop Med Hyg. 2021;105(6):1747-1758. DOI: 10.4269/ajtmh.21-0210

Lautu-Gumal D, Razook Z, Koleala T, Nate E, McEwen S, Timbi D, Hetzel M.W, Lavu E, Tefuarani N, Makita L, Kazura J, Mueller I, Pomat W, Laman M, Robinson L.J, Barry A.E. Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018. Int J Parasitol Drugs Drug Resist. 2021;16:188-193. DOI: 10.1016/j.ijpddr.2021.06.004

Lee T.T, Omoluabi E, Ayodeji K, Yusuf O, Okon C, Brunner N.C, Delvento G, Signorell A, Lambiris M, Kwiatkowski M, Burri C, Lengeler C, Emedo E, Cheshi F, Hetzel M.W. Treatment-seeking for children with suspected severe malaria attending community health workers and primary health centres in Adamawa State, Nigeria. medRxiv. 2021(in press). DOI: 10.1101/2021.12.01.21267130

Rodríguez-Rodríguez D, Katusele M, Auwun A, Marem M, Robinson L.J, Laman M, Hetzel M.W, Pulford J. Human behavior, livelihood, and malaria transmission in two sites of Papua New Guinea. J Infect Dis. 2021;223(Suppl. 2):S171-S186. DOI: 10.1093/infdis/jiaa402

Seidahmed O.M.E, Kurumop S, Jamea-Maiasa S, Timbi D, Tandrapah A, Hetzel M, Pomat W. Papua New Guinea malaria indicator survey 2019-2020: final report on malaria prevention, infection prevalence, and treatment-seeking. Goroka: Papua New Guinea Institute of Medical Research, PNGIMR, 2021

Grossenbacher B, Holzschuh A, Hofmann N.E, Omar K.A, Stuck L, Fakih B.S, Ali A, Yukich J, Hetzel M.W, Felger I. Molecular methods for tracking residual Plasmodium falciparum transmission in a close-to-elimination setting in Zanzibar. Malar J. 2020;19:50. DOI: 10.1186/s12936-020-3127-x

Hetzel M. PNG’s health data: too much of a good thing – part two. Australia: Devpolicy Blog, 2020

Hetzel M. PNG’s health data: too much of a good thing – part one. Australia: Devpolicy Blog, 2020

Hetzel M.W, Bonfoh B. Towards more balanced representation in Lancet commissions. Lancet. 2020;395(10238):1693-1694. DOI: 10.1016/S0140-6736(20)30617-6

Hetzel M.W, Chitnis N. Reducing malaria transmission with reactive focal interventions. Lancet. 2020;395(10233):1317-1319. DOI: 10.1016/S0140-6736(20)30678-4

Miotto O, Sekihara M, Tachibana S.I, Yamauchi M, Pearson R.D, Amato R, Goncalves S, Mehra S, Noviyanti R, Marfurt J, Auburn S, Price R.N, Mueller I, Ikeda M, Mori T, Hirai M, Tavul L, Hetzel M.W, Laman M, Barry A.E, Ringwald P, Ohashi J, Hombhanje F, Kwiatkowski D.P, Mita T. Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea. PLoS Pathog. 2020;16(12):e1009133. DOI: 10.1371/journal.ppat.1009133

Stuck L, Fakih B.S, Al-mafazy A.H, Hofmann N.E, Holzschuh A, Grossenbacher B, Bennett A, Cotter C, Reaves E, Ali A, Van der Horst T, Felger I, Hetzel M.W, Yukich J. Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar. Int J Infect Dis. 2020;97:337-346. DOI: 10.1016/j.ijid.2020.06.017

Van der Horst T, Al-mafazy A.W, Fakih B.S, Stuck L, Ali A, Yukich J, Hetzel M.W. Operational coverage and timeliness of reactive case detection for malaria elimination in Zanzibar, Tanzania. Am J Trop Med Hyg. 2020;102(2):298-306. DOI: 10.4269/ajtmh.19-0505

Brunner N.C, Chacky F, Mandike R, Mohamed A, Runge M, Thawer S.G, Ross A, Vounatsou P, Lengeler C, Molteni F, Hetzel M.W. The potential of pregnant women as a sentinel population for malaria surveillance. Malar J. 2019;18:370. DOI: 10.1186/s12936-019-2999-0

Evaluation Task Force of Roll Back Malaria’s Monitoring and Evaluation Reference Group. Framework for evaluating national malaria programs in moderate and low transmission settings. Chapel Hill, NC, USA: MEASURE Evaluation, 2019

Rodriguez-Rodriguez D, Maraga S, Jamea-Maiasa S, Tandrapah A, Makita L, Siba P.M, Mueller I, Pulford J, Hetzel M. Mapping routine malaria incidence at village level for targeted control in Papua New Guinea. Geospat Health. 2019;14(2):357-360. DOI: 10.4081/gh.2019.798

Rodriguez-Rodriguez D, Maraga S, Lorry L, Robinson L.J, Siba P.M, Mueller I, Pulford J, Ross A, Hetzel M.W. Repeated mosquito net distributions, improved treatment, and trends in malaria cases in sentinel health facilities in Papua New Guinea. Malar J. 2019;18:364. DOI: 10.1186/s12936-019-2993-6

Fola A.A, Nate E, Harrison G.L.A, Barnades C, Hetzel M.W, Iga J, Siba P, Mueller I, Barry A.E. Nationwide genetic surveillance of Plasmodium vivax in Papua New Guinea reveals heterogeneous transmission dynamics and routes of migration amongst subdivided populations. Infect Genet Evol. 2018;58:83-95. DOI: 10.1016/j.meegid.2017.11.028

Hetzel M. Management of severe malaria cases learnings and challenges from the field. 67th Annual Meeting of the American Society of Tropical Medicine and Hygiene. New Orlean, USA: The American Society of Tropical Medicine and Hygiene, 2018

Hetzel M.W, Genton B. Mass drug administration for malaria elimination: do we understand the settings well enough?. BMC Med. 2018;16:239. DOI: 10.1186/s12916-018-1230-4

Hetzel M.W, Saweri O.P.M, Kuadima J.J, Smith I, Ura Y, Tandrapah A, Jamea-Maiasa S, Siba P.M, Pulford J. Papua New Guinea malaria indicator survey 2016-2017: malaria prevention, infection and treatment. Goroka: Papua New Guinea Institute of Medical Research, 2018

Koimbu G, Czeher C, Katusele M, Sakur M, Kilepak L, Tandrapah A, Hetzel M.W, Pulford J, Robinson L, Karl S. Status of insecticide resistance in Papua New Guinea: an update from nation-wide monitoring of anopheles mosquitoes. Am J Trop Med Hyg. 2018;98(1):162-165. DOI: 10.4269/ajtmh.17-0454

Lengeler C, Hetzel M, Signorell A, Awor P, Tshefu A, Okitawutshu J, Omoluabi E, Nepomnyashchiy L, Fast J, Ramachandra S, Goldstein R, Buj V, Burri C. Introducing rectal artesunate in community settings and evaluating its impact. 7th MIM Pan African Malaria Conference. Dakar, Senegal, 2018

Pulford J, Kurumop S, Mueller I, Siba P.M, Hetzel M.W. The impact of the scale-up of malaria rapid diagnostic tests on the routine clinical diagnosis procedures for febrile illness: a series of repeated cross-sectional studies in Papua New Guinea. Malar J. 2018;17:202. DOI: 10.1186/s12936-018-2351-0

Pulford J, Saweri O.P.M, Jeffery C, Siba P.M, Mueller I, Hetzel M.W. Does test-based prescription of evidence-based treatment for malaria improve treatment seeking and satisfaction? Findings of repeated cross-sectional surveys in Papua New Guinea. BMJ Glob Health. 2018;3(6):e000915. DOI: 10.1136/bmjgh-2018-000915

Signorell A, Hetzel M, Awor P, Tshefu A, Okitawutshu J, Omoluabi E, Nepomnyashchiy L, Burri C, Lengeler C. CARAMAL: addressing the remaining burden of malaria deaths by optimizing the use of rectla artesunate. 7th MIM Pan African Malaria Conference. Dakar, Senegal, 2018

Tavul L, Hetzel M.W, Teliki A, Walsh D, Kiniboro B, Rare L, Pulford J, Siba P.M, Karl S, Makita L, Robinson L, Kattenberg J.H, Laman M, Oswyn G, Mueller I. Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria in Papua New Guinea. Malar J. 2018;17:350. DOI: 10.1186/s12936-018-2494-z

White M.T, Walker P, Karl S, Hetzel M.W, Freeman T, Waltmann A, Laman M, Robinson L.J, Ghani A, Mueller I. Mathematical modelling of the impact of expanding levels of malaria control interventions on Plasmodium vivax. Nat Commun. 2018;9(1):3300. DOI: 10.1038/s41467-018-05860-8

Fola A.A, Abby Harrison G.L, Hazairin M.H, Barnadas C, Hetzel M.W, Iga J, Siba P.M, Mueller I, Barry A.E. Higher complexity of infection and genetic diversity of Plasmodium vivax than Plasmodium falciparum across all malaria transmission zones of Papua New Guinea. Am J Trop Med Hyg. 2017;96(3):630-641. DOI: 10.4269/ajtmh.16-0716

Hetzel M.W, Pulford J, Ura Y, Jamea-Maiasa S, Tandrapah A, Tarongka N, Lorry L, Robinson L.J, Lilley K, Makita L, Siba P.M, Mueller I. Insecticide-treated nets and malaria prevalence, Papua New Guinea, 2008–2014. Bull World Health Organ. 2017;95:695-705. DOI: 10.2471/BLT.16.189902

Koimbu G, Czeher C, Tandrapah A, Siba P, Hetzel M, Pulford J, Robinson L, Karl S. Insecticide resistance monitoring: report on phenotypic resistance of anophelines to deltamethrin, lambda-cyhalothrin and DDT (2016). Goroka: Papa New Guinea Institute of Medical Research, 2017

Kuadima J.J, Timinao L, Naidi L, Tandrapah A, Hetzel M.W, Czeher C, Pulford J. Long-term acceptability, durability and bio-efficacy of ZeroVector® durable lining for vector control in Papua New Guinea. Malar J. 2017;16:93. DOI: 10.1186/s12936-017-1742-y

Saweri O.P, Hetzel M.W, Mueller I, Siba P.M, Pulford J. The treatment of non-malarial febrile illness in Papua New Guinea: findings from cross sectional and longitudinal studies of health worker practice. BMC Health Serv Res. 2017;17:10. DOI: 10.1186/s12913-016-1965-6

Thomsen E.K, Koimbu G, Pulford J, Jamea-Maiasa S, Ura Y, Keven J.B, Siba P.M, Mueller I, Hetzel M.W, Reimer L.J. Mosquito behavior change after distribution of bednets results in decreased protection against malaria exposure. J Infect Dis. 2017;215(5):790-797. DOI: 10.1093/infdis/jiw615

Hetzel M.W, Reimer L.J, Gideon G, Koimbu G, Barnadas C, Makita L, Siba P.M, Mueller I. Changes in malaria burden and transmission in sentinel sites after the roll-out of long-lasting insecticidal nets in Papua New Guinea. Parasit Vectors. 2016;9:340. DOI: 10.1186/s13071-016-1635-x

Kurumop S.F, Tandrapah A, Hetzel M.W, Siba P.M, Mueller I, Pulford J. The Papua New Guinea national malaria control program: health facility surveys 2010-2016. Goroka: Papua New Guinea Institute of Medical Research, 2016

Ménard D, Khim N, Beghain J, Adegnika A.A, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos M.D, Cao J, Chen J.H, Collet L, Cui L, Thakur G.D, Dieye A, Djalle D, Dorkenoo M.A, Eboumbou-Moukoko C.E, Espino F.E, Fandeur T, Ferreira-da-Cruz M.F, Fola A.A, Fuehrer H.P, Hassan A.M, Herrera S, Hongvanthong B, Houze S, Ibrahim M.L, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner P.G, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati J.B, Menard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niare K, Noedl H, Ouedraogo J.B, Pillai D.R, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silue K.D, Sirima S.B, Sutherland C, Syafruddin D, Tahar R, Tang L.H, Toure O.A, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale J.C, Stokes B, Straimer J, Witkowski B, Fidock D.A, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O, Karma Consortium. A worldwide map of Plasmodium falciparum K13-propeller polymorphisms. N Engl J Med. 2016;374(25):2453-2464. DOI: 10.1056/NEJMoa1513137

Pulford J, Smith I, Mueller I, Siba P.M, Hetzel M.W. Health worker compliance with a 'test and treat' malaria case management protocol in Papua New Guinea. PLoS One. 2016;11(7):e0158780. DOI: 10.1371/journal.pone.0158780

Reimer L.J, Thomsen E.K, Koimbu G, Keven J.B, Mueller I, Siba P.M, Kazura J.W, Hetzel M.W, Zimmerman P.A. Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea. Malar J. 2016;15:25. DOI: 10.1186/s12936-015-1067-7

Tavul L, Hetzel M.W, Siba P, Makita L, Karl S, Pulford J, Mueller I. The efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria in Papua New Guinea: 2012-2014. Papua New Guinea: Papua New Guinea Institute of Medical Research, 2016

Hetzel M.W, Morris H, Tarongka N, Barnadas C, Pulford J, Makita L, Siba P.M, Mueller I. Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets. Trop Med Int Health. 2015;20(12):1745-1755. DOI: 10.1111/tmi.12616

Hetzel M.W, Pulford J, Timbi D, Koimbu G, Barnadas C, Siba P.M, Mueller I. Dynamic changes in prevalence and incidence of malaria after intensifying control across Papua New Guinea. Trop Med Int Health, 2015;20(Suppl. 1):26

Pulford J, Smith J, Mueller I, Siba P.M, Hetzel M.W. Impact of changed fever case management practice on patients' self-reported treatment experience. Trop Med Int Health, 2015;20(Suppl. 1):417-418. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Pulford J, Tandrapah A, Siba P.M, Mueller I, Hetzel M.W. Report on time-trend data derived from malaria rapid diagnostic testing in sentinel health facilities, 2008-2015 (PNGIMR Malaria Sentinel Surveillance Program). Goroka: Papua New Guinea Institute of Medical Research, 2015

Roll Back Malaria Partnership. Action and investment to defeat malaria 2016-2030: for a malaria-free world. Geneva: World Health Organization, 2015

Angwin A, Hetzel M.W, Mueller I, Siba P.M, Pulford J. A qualitative study of how affected individuals or their caregivers respond to suspected malaria infection in rural Papua New Guinea. PNG Med J. 2014;57(1-4):30-38

Bande G, Hetzel M.W, Iga J, Barnadas C, Mueller I, Siba P.M, Horwood P.F. An investigation into febrile illnesses of unknown aetiology in Wipim, Papua New Guinea. PNG Med J. 2014;57(1-4):52-58