Publications
Jacobson K.B, Röltgen K, Lam B, Nayebare P, Kakuru A, Kizza J, Aguti M, Nankya F, Briggs J, Takahashi S, Greenhouse B, Rodriguez-Barraquer I, van der Ploeg K, Wohlstadter J.N, Sigal G.B, Roh M.E, Nankabirwa J.I, Cuu G, Gaw S.L, Rosenthal P.J, Kamya M.R, Ssewanyana I, Dorsey G, Boyd S.D, Jagannathan P. Gestational SARS-CoV-2 infection in a Ugandan birth cohort: high incidence, mild maternal disease, and evidence of association with transient infant stunting. Am J Trop Med Hyg. 2024;111(5):1107-1117. DOI: 10.4269/ajtmh.23-0801
Röltgen K, Boyd S.D. Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning. Annu Rev Pathol. 2024;19:69-97. DOI: 10.1146/annurev-pathmechdis-031521-042754
Gao F, Mallajoysula V, Arunachalam P.S, van der Ploeg K, Manohar M, Röltgen K, Yang F, Wirz O, Hoh R, Haraguchi E, Lee J.Y, Willis R, Ramachandiran V, Li J, Kathuria K.R, Li C, Lee A.S, Shah M.M, Sindher S.B, Gonzalez J, Altman J.D, Wang T.T, Boyd S.D, Pulendran B, Jagannathan P, Nadeau K.C, Davis M.M. Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8(+) T cell responses post SARS-CoV-2 infection. Immunity. 2023;56(4):864-878 e4. DOI: 10.1016/j.immuni.2023.03.005
Goldman J.D, Wang K, Röltgen K, Nielsen S.C.A, Roach J.C, Naccache S.N, Yang F, Wirz O.F, Yost K.E, Lee J.Y, Chun K, Wrin T, Petropoulos C.J, Lee I, Fallen S, Manner P.M, Wallick J.A, Algren H.A, Murray K.M, Hadlock J, Chen D, Dai C.L, Yuan D, Su Y, Jeharajah J, Berrington W.R, Pappas G.P, Nyatsatsang S.T, Greninger A.L, Satpathy A.T, Pauk J.S, Boyd S.D, Heath J.R. Reinfection with SARS-CoV-2 and waning humoral immunity: a case report. Vaccines (Basel). 2022;11(1):5. DOI: 10.3390/vaccines11010005
Jia X, Cao S, Lee A.S, Manohar M, Sindher S.B, Ahuja N, Artandi M, Blish C.A, Blomkalns A.L, Chang I, Collins W.J, Desai M, Din H.N, Do E, Fernandes A, Geng L.N, Rosenberg-Hasson Y, Mahoney M.R, Glascock A.L, Chan L.Y, Fong S.Y, CLIAHUB Consortium, Chan Zuckerberg Biohub, Phelps M, Raeber O, Stanford COVID-19 Biobank Study Group, Purington N, Röltgen K, Rogers A.J, Snow T, Wang T.T, Solis D, Vaughan L, Verghese M, Maecker H, Wittman R, Puri R, Kistler A, Yang S, Boyd S.D, Pinsky B.A, Chinthrajah S, Nadeau K.C. Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome. JCI Insight. 2022;7(13):e156713. DOI: 10.1172/jci.insight.156713
Pillet S, Arunachalam P.S, Andreani G, Golden N, Fontenot J, Aye P.P, Röltgen K, Lehmicke G, Gobeil P, Dubé C, Trépanier S, Charland N, D'Aoust M.A, Russell-Lodrigue K, Monjure C, Blair R.V, Boyd S.D, Bohm R.P, Rappaport J, Villinger F, Landry N, Pulendran B, Ward B.J. Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates. Cell Mol Immunol. 2022;19(2):222-233. DOI: 10.1038/s41423-021-00809-2
Pluschke G,Röltgen K, eds. Mycobacterium ulcerans: methods and protocols. New York, NY: Humana Press, 2022. DOI: 10.1007/978-1-0716-1779-3
Edited Book
Pluschke G, Röltgen K. Overview: development of drugs against Mycobacterium ulcerans. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 185-187. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_17
Pluschke G, Röltgen K. Preface. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, V-VI. New York, NY: Humana, 2022. DOI: 10.1007/978-1-0716-1779-3_1
Book Section
Röltgen K, Johnson P.D.R, Pluschke G. Epidemiology of Buruli ulcer. In: Nunzi E,Massone C,Portaels F, eds. Leprosy and Buruli ulcer. A practical guide, 541-550. Cham: Springer Nature, 2022. DOI: 10.1007/978-3-030-89704-8_47
Book Section
Röltgen K, Nielsen S.C.A, Silva O, Younes S.F, Zaslavsky M, Costales C, Yang F, Wirz O.F, Solis D, Hoh R.A, Wang A, Arunachalam P.S, Colburg D, Zhao S, Haraguchi E, Lee A.S, Shah M.M, Manohar M, Chang I, Gao F, Mallajosyula V, Li C, Liu J, Shoura M.J, Sindher S.B, Parsons E, Dashdorj N.J, Dashdorj N.D, Monroe R, Serrano G.E, Beach T.G, Chinthrajah R.S, Charville G.W, Wilbur J.L, Wohlstadter J.N, Davis M.M, Pulendran B, Troxell M.L, Sigal G.B, Natkunam Y, Pinsky B.A, Nadeau K.C, Boyd S.D. Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination. Cell. 2022;185(6):1025-1040 e14. DOI: 10.1016/j.cell.2022.01.018
Röltgen K, Pluschke G. Overview: Mycobacterium ulcerans disease (Buruli ulcer). In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 3-6. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_1
Röltgen K, Pluschke G. Overview: mycolactone, the macrolide toxin of Mycobacterium ulcerans. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 105-108. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_11
Serrano G.E, Walker J.E, Tremblay C, Piras I.S, Huentelman M.J, Belden C.M, Goldfarb D, Shprecher D, Atri A, Adler C.H, Shill H.A, Driver-Dunckley E, Mehta S.H, Caselli R, Woodruff B.K, Haarer C.F, Ruhlen T, Torres M, Nguyen S, Schmitt D, Rapscak S.Z, Bime C, Peters J.L, Alevritis E, Arce R.A, Glass M.J, Vargas D, Sue L.I, Intorcia A.J, Nelson C.M, Oliver J, Russell A, Suszczewicz K.E, Borja C.I, Cline M.P, Hemmingsen S.J, Qiji S, Hobgood H.M, Mizgerd J.P, Sahoo M.K, Zhang H, Solis D, Montine T.J, Berry G.J, Reiman E.M, Röltgen K, Boyd S.D, Pinsky B.A, Zehnder J.L, Talbot P, Desforges M, DeTure M, Dickson D.W, Beach T.G. SARS-CoV-2 brain regional detection, histopathology, gene expression, and immunomodulatory changes in decedents with COVID-19. J Neuropathol Exp Neurol. 2022;81(9):666-695. DOI: 10.1093/jnen/nlac056
Arunachalam P.S, Walls A.C, Golden N, Atyeo C, Fischinger S, Li C, Aye P, Navarro M.J, Lai L, Edara V.V, Röltgen K, Rogers K, Shirreff L, Ferrell D.E, Wrenn S, Pettie D, Kraft J.C, Miranda M.C, Kepl E, Sydeman C, Brunette N, Murphy M, Fiala B, Carter L, White A.G, Trisal M, Hsieh C.L, Russell-Lodrigue K, Monjure C, Dufour J, Spencer S, Doyle-Meyers L, Bohm R.P, Maness N.J, Roy C, Plante J.A, Plante K.S, Zhu A, Gorman M.J, Shin S, Shen X, Fontenot J, Gupta S, O'Hagan D.T, Van Der Most R, Rappuoli R, Coffman R.L, Novack D, McLellan J.S, Subramaniam S, Montefiori D, Boyd S.D, Flynn J.L, Alter G, Villinger F, Kleanthous H, Rappaport J, Suthar M.S, King N.P, Veesler D, Pulendran B. Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. Nature. 2021;594(7862):253-258. DOI: 10.1038/s41586-021-03530-2
Dashdorj N.J, Wirz O.F, Röltgen K, Haraguchi E, Buzzanco A.S, Sibai M, Wang H, Miller J.A, Solis D, Sahoo M.K, Arunachalam P.S, Lee A.S, Shah M.M, Liu J, Byambabaatar S, Bat-Ulzii P, Enkhbat A, Batbold E, Zulkhuu D, Ochirsum B, Khurelsukh T, Dalantai G, Burged N, Baatarsuren U, Ariungerel N, Oidovsambuu O, Bungert A.S, Genden Z, Yagaanbuyant D, Mordorj A, Pulendran B, Chinthrajah S, Nadeau K.C, Jardetzky T, Wilbur J.L, Wohlstadter J.N, Sigal G.B, Pinsky B.A, Boyd S.D, Dashdorj N.D. Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia. Cell Host Microbe. 2021;29(12):1738-1743 e4. DOI: 10.1016/j.chom.2021.11.004
Day C.J, Röltgen K, Pluschke G, Jennings M.P. The cell surface protein MUL_3720 confers binding of the skin pathogen Mycobacterium ulcerans to sulfated glycans and keratin. PLoS Negl Trop Dis. 2021;15(2):e0009136. DOI: 10.1371/journal.pntd.0009136
Hogan C.A, Gombar S, Wang H, Röltgen K, Shi R.Z, Holubar M, Chang S.I, Lee G.M, Boyd S.D, Zehnder J, Pinsky B.A. Large-scale testing of asymptomatic healthcare personnel for severe acute respiratory syndrome coronavirus 2. Emerg Infect Dis. 2021;27(1):250-4. DOI: 10.3201/eid2701.203892
Lawrence L, Stevens B.A, Sahoo M.K, Huang C, Yamamoto F, Röltgen K, Wirz O, Zehnder J, Shi R.Z, Boyd S.D, Schoolnik G, Pinsky B.A, Hogan C.A. Plasma as an alternative COVID-19 diagnostic specimen in a hospitalized patient negative for SARS-CoV-2 by nasopharyngeal swab. Diagn Microbiol Infect Dis. 2021;100(3):115365. DOI: 10.1016/j.diagmicrobio.2021.115365
Nguyen K.D, Wirz O.F, Röltgen K, Pandey S, Tolentino L, Boyd S.D, Pham T.D. Efficient identification of high-titer anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody plasma samples by pooling method. Arch Pathol Lab Med. 2021;145(10):1221-1227. DOI: 10.5858/arpa.2021-0215-SA
Röltgen K, Boyd S.D. Antibody and B cell responses to SARS-CoV-2 infection and vaccination. Cell Host Microbe. 2021;29(7):1063-1075. DOI: 10.1016/j.chom.2021.06.009
Rosser J.I, Röltgen K, Dymock M, Shepard J, Martin A, Hogan C.A, Blomkalns A, Mathew R, Parsonnet J, Pinsky B.A, Maldonado Y.A, Boyd S.D, Chang S.I, Holubar M, Stanford Healthcare COVID-19 Workforce Response Group. Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroprevalence in healthcare personnel in northern California early in the coronavirus disease 2019 (COVID-19) pandemic. Infect Control Hosp Epidemiol. 2021;42(9):1053-1059. DOI: 10.1017/ice.2020.1358
Sibai M, Solis D, Röltgen K, Stevens B.A, Mfuh K.O, Sahoo M.K, Shi R.Z, Zehnder J, Boyd S.D, Pinsky B.A. Evaluation of SARS-CoV-2 total antibody detection via a lateral flow nanoparticle fluorescence immunoassay. J Clin Virol. 2021;139:104818. DOI: 10.1016/j.jcv.2021.104818
Truong T.T, Ryutov A, Pandey U, Yee R, Goldberg L, Bhojwani D, Aguayo-Hiraldo P, Pinsky B.A, Pekosz A, Shen L, Boyd S.D, Wirz O.F, Röltgen K, Bootwalla M, Maglinte D.T, Ostrow D, Ruble D, Han J.H, Biegel J.A, Li M, Huang C, Sahoo M.K, Pannaraj P.S, O'Gorman M, Judkins A.R, Gai X, Dien Bard J. Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: a consecutive case series. EBioMedicine. 2021;67:103355. DOI: 10.1016/j.ebiom.2021.103355
Wagar L.E, Salahudeen A, Constantz C.M, Wendel B.S, Lyons M.M, Mallajosyula V, Jatt L.P, Adamska J.Z, Blum L.K, Gupta N, Jackson K.J.L, Yang F, Röltgen K, Roskin K.M, Blaine K.M, Meister K.D, Ahmad I.N, Cortese M, Dora E.G, Tucker S.N, Sperling A.I, Jain A, Davies D.H, Felgner P.L, Hammer G.B, Kim P.S, Robinson W.H, Boyd S.D, Kuo C.J, Davis M.M. Modeling human adaptive immune responses with tonsil organoids. Nat Med. 2021;27:125-135. DOI: 10.1038/s41591-020-01145-0
Wang H, Hogan C.A, Verghese M, Solis D, Sibai M, Huang C, Röltgen K, Stevens B.A, Yamamoto F, Sahoo M.K, Zehnder J, Boyd S.D, Pinsky B.A. SARS-CoV-2 nucleocapsid plasma antigen for diagnosis and monitoring of COVID-19. Clin Chem. 2021;68(1):204-213. DOI: 10.1093/clinchem/hvab216
Wang H, Wiredja D, Yang L, Bulterys P.L, Costales C, Röltgen K, Manalac J, Yee J, Zehnder J, Shi R.Z, Boyd S.D, Pinsky B.A. Case-control study of individuals with discrepant nucleocapsid and spike protein SARS-CoV-2 IgG results. Clin Chem. 2021;67(7):977-986. DOI: 10.1093/clinchem/hvab045
Wirz O.F, Röltgen K, Stevens B.A, Pandey S, Sahoo M.K, Tolentino L, Verghese M, Nguyen K, Hunter M, Snow T.T, Singh A.R, Blish C.A, Cochran J.R, Zehnder J.L, Nadeau K.C, Pinsky B.A, Pham T.D, Boyd S.D. Use of outpatient-derived COVID-19 convalescent plasma in COVID-19 patients before seroconversion. Front Immunol. 2021;12:739037. DOI: 10.3389/fimmu.2021.739037
Yang F, Nielsen S.C.A, Hoh R.A, Röltgen K, Wirz O.F, Haraguchi E, Jean G.H, Lee J.Y, Pham T.D, Jackson K.J.L, Roskin K.M, Liu Y, Nguyen K, Ohgami R.S, Osborne E.M, Nadeau K.C, Niemann C.U, Parsonnet J, Boyd S.D. Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Science. 2021;372(6543):738-741. DOI: 10.1126/science.abf6648
Nielsen S.C.A, Yang F, Jackson K.J.L, Hoh R.A, Röltgen K, Jean G.H, Stevens B.A, Lee J.Y, Rustagi A, Rogers A.J, Powell A.E, Hunter M, Najeeb J, Otrelo-Cardoso A.R, Yost K.E, Daniel B, Nadeau K.C, Chang H.Y, Satpathy A.T, Jardetzky T.S, Kim P.S, Wang T.T, Pinsky B.A, Blish C.A, Boyd S.D. Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2. Cell Host Microbe. 2020;28(4):516-525 e5. DOI: 10.1016/j.chom.2020.09.002
Pham T.D, Huang C, Wirz O.F, Röltgen K, Sahoo M.K, Layon A, Pandey S, Foung S.K, Boyd S.D, Pinsky B.A. SARS-CoV-2 RNAemia in a healthy blood donor 40 days after respiratory illness resolution. Ann Intern Med. 2020;173(10):853-854. DOI: 10.7326/L20-0725
Röltgen K, Pluschke G, Spencer J.S, Brennan P.J, Avanzi C. The immunology of other mycobacteria: M. ulcerans, M. leprae. Semin Immunopathol. 2020;42(3):333-353. DOI: 10.1007/s00281-020-00790-4
Röltgen K, Pluschke G. Buruli ulcer: the efficacy of innate immune defense may be a key determinant for the outcome of infection with Mycobacterium ulcerans. Front Microbiol. 2020;11:1018. DOI: 10.3389/fmicb.2020.01018
Röltgen K, Powell A.E, Wirz O.F, Stevens B.A, Hogan C.A, Najeeb J, Hunter M, Wang H, Sahoo M.K, Huang C, Yamamoto F, Manohar M, Manalac J, Otrelo-Cardoso A.R, Pham T.D, Rustagi A, Rogers A.J, Shah N.H, Blish C.A, Cochran J.R, Jardetzky T.S, Zehnder J.L, Wang T.T, Narasimhan B, Gombar S, Tibshirani R, Nadeau K.C, Kim P.S, Pinsky B.A, Boyd S.D. Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome. Sci Immunol. 2020;5(54):eabe0240. DOI: 10.1126/sciimmunol.abe0240
Pluschke G,Röltgen K, eds. Buruli ulcer: Mycobacterium ulcerans disease. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4
Edited Book
Röltgen K, Cruz I, Ndung'u J.M, Pluschke G. Laboratory diagnosis of Buruli ulcer: challenges and future perspectives. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 183-202. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_10
Book Section
Röltgen K, Pluschke G. Buruli ulcer: history and disease burden. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 1-42. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_1
Book Section
Tabah E.N, Johnson C.R, Degnonvi H, Pluschke G, Röltgen K. Buruli ulcer in Africa. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 43-60. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_2
Book Section
Lamelas A, Hamid A.M, Dangy J.P, Hauser J, Jud M, Röltgen K, Hodgson A, Junghanss T, Harris S.R, Parkhill J, Bentley S.D, Pluschke G. Loss of genomic diversity in a Neisseria meningitidis clone through a colonization bottleneck. Genome Biol Evol. 2018;10(8):2102-2109. DOI: 10.1093/gbe/evy152
Pinho-Nascimento C.A, Bratschi M.W, Höfer R, Soares C.C, Warryn L, Pecerska J, Minyem J.C, Paixão I.C.N.P, Baroni de Moraes M.T, Um Boock A, Niel C, Pluschke G, Röltgen K. Transmission of hepatitis B and D viruses in an African rural community. mSystems. 2018;3(5):e00120-18. DOI: 10.1128/mSystems.00120-18
Röltgen K, Rose N, Ruggieri A, Warryn L, Scherr N, Pinho-Nascimento C.A, Tamborrini M, Jaenisch T, Pluschke G. Development of dengue virus serotype-specific NS1 capture assays for the rapid and highly sensitive identification of the infecting serotype in human sera. J Immunol. 2018;200(200):3857-3866. DOI: 10.4049/jimmunol.1701790
Lamelas A, Hauser J, Dangy J.P, Hamid A.M, Roltgen K, Abdul Sater M.R, Hodgson A, Sie A, Junghanss T, Harris S.R, Parkhill J, Bentley S.D, Pluschke G. Emergence and genomic diversification of a virulent serogroup W:ST-2881(CC175) Neisseria meningitidis clone in the African meningitis belt. Microb Genom. 2017;3(8):e000120. DOI: 10.1099/mgen.0.000120
Röltgen K, Pluschke G, Johnson P.D.R, Fyfe J. Mycobacterium ulcerans DNA in bandicoot excreta in Buruli ulcer-endemic area, Northern Queensland, Australia. Emerg Infect Dis. 2017;23(12):2042-2045. DOI: 10.3201/eid2312.170780
Aboagye S.Y, Danso E, Ampah K.A, Nakobu Z, Asare P, Otchere I.D, Röltgen K, Yirenya-Tawiah D, Yeboah-Manu D. Isolation of nontuberculous Mycobacteria from the environment of Buruli ulcer endemic communities in Ghana. Appl Environ Microbiol. 2016;82(14):4320-4309. DOI: 10.1128/AEM.01002-16
Ampah K.A, Asare P, Binnah D.D, Maccaulley S, Opare W, Röltgen K, Pluschke G, Yeboah-Manu D. Burden and historical trend of Buruli ulcer prevalence in selected communities along the Offin River of Ghana. PLoS Negl Trop Dis. 2016;10(4):e0004603. DOI: 10.1371/journal.pntd.0004603
Ampah K.A, Nickel B, Asare P, Ross A, De-Graft D, Kerber S, Spallek R, Singh M, Pluschke G, Yeboah-Manu D, Röltgen K. A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans. PLoS Negl Trop Dis. 2016;10:e0004387. DOI: 10.1371/journal.pntd.0004387
Ampah K.A, Pinho-Nascimento C.A, Kerber S, Asare P, De-Graft D, Adu-Nti F, Paixao I.C, Niel C, Yeboah-Manu D, Pluschke G, Röltgen K. Limited genetic diversity of hepatitis B virus in the general population of the Offin River valley in Ghana. PLoS One. 2016;11(6):e0156864. DOI: 10.1371/journal.pone.0156864
Lamelas A, Ampah K.A, Aboagye S, Kerber S, Danso E, Asante-Poku A, Asare P, Parkhill J, Harris S.R, Pluschke G, Yeboah-Manu D, Röltgen K. Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River valley of Ghana. PLoS Negl Trop Dis. 2016;10(7):e0004856. DOI: 10.1371/journal.pntd.0004856
Rose N, Pinho-Nascimento C.A, Ruggieri A, Favuzza P, Tamborrini M, Roth H, Baroni de Moraes M.T, Matile H, Janisch T, Pluschke G, Roltgen K. Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization. BMC Biotechnol. 2016;16:83. DOI: 10.1186/s12896-016-0314-5
Aboagye S.Y, Ampah K, Asare P, Danso E.K, Darko I.O, Röltgen K, Pluschke G, Fyfe J, Yeboah-Manu D. Understanding the ecology of Mycobacterium ulcerans to facilitate strategies for prevention and control of Buruli ulcer in Ghana. Trop Med Int Health, 2015;20(Suppl. 1):242. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland
Conference Paper
Dreyer A, Röltgen K, Dangy J.P, Ruf M.T, Scherr N, Bolz M, Tobias N.J, Moes C, Vettiger A, Stinear T.P, Pluschke G. Identification of the Mycobacterium ulcerans protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer. PLoS Negl Trop Dis. 2015;9(2):e0003477. DOI: 10.1371/journal.pntd.0003477
Röltgen K, Dreyer A, Dangy J.P, Scherr N, Ruf M.T, Kerber S, Ndung'u J.M, Pluschke G. On the way to point-of-care diagnostics for Buruli ulcer: an antigen capture approach. Trop Med Int Health, 2015;20(Suppl. 1):55
Conference Paper
Röltgen K, Pluschke G. Mycobacterium ulcerans disease (Buruli ulcer): potential reservoirs and vectors. Curr Clin Micro Rpt. 2015;2:35-43. DOI: 10.1007/s40588-015-0013-3
Journal Article
Röltgen K, Pluschke G. Epidemiology and disease burden of Buruli ulcer: a review. Res Rep Trop Med. 2015;6:59-73. DOI: 10.2147/RRTM.S62026
Journal Article
Sater M.R, Lamelas A, Wang G, Clark T.A, Röltgen K, Mane S, Korlach J, Pluschke G, Schmid C.D. DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates. PLoS One. 2015;10(12):e0144612. DOI: 10.1371/journal.pone.0144612
Scherr N, Ramon-Garcia S, Röltgen K, Thompson C.J, Witschel M, Pluschke G. Re-purposing antimicrobial compounds as a promising approach for the identification of scaffolds with activity against Mycobacterium ulcerans. Trop Med Int Health, 2015;20(Suppl. 1):243. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland
Conference Paper
Lamelas A, Harris S.R, Röltgen K, Dangy J.P, Hauser J, Kingsley R.A, Connor T.R, Sie A, Hodgson A, Dougan G, Parkhill J, Bentley S.D, Pluschke G. Emergence of a new epidemic Neisseria meningitidis serogroup A clone in the African meningitis belt: high-resolution picture of genomic changes that mediate immune evasion. mBio. 2014;5(5):e01974-14. DOI: 10.1128/mBio.01974-14
Röltgen K, Bratschi M.W, Ross A, Aboagye S.Y, Ampah K.A, Bolz M, Andreoli A, Pritchard J, Minyem J.C, Noumen D, Koka E, Um Boock A, Yeboah-Manu D, Pluschke G. Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children. PLoS Negl Trop Dis. 2014;8(5):e2904. DOI: 10.1371/journal.pntd.0002904
Vettiger A, Scherr N, Ruf M.T, Röltgen K, Pluschke G. Localization of mycobacterial antigens by immunofluorescence staining of agarose embedded cells. Mycobact Dis. 2014;4(3):1000150. DOI: 10.4172/2161-1068.1000150
Journal Article
Röltgen K, Dreyer A, Dangy J.P, Bratschi M.W, Ruf M.T, Kerber S, Yeboah-Manu D, Pluschke G. Point-of-care diagnosis for the emerging skin disease, Buruli ulcer: an antigen capture approach. Am J Trop Med Hyg, 2013;89(5 Suppl.):357
Conference Paper
Röltgen K, Assan-Ampah K, Danso E, Yeboah-Manu D, Pluschke G. Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans. PLoS Negl Trop Dis. 2012;6(11):e1904. DOI: 10.1371/journal.pntd.0001904
Röltgen K, Stinear T.P, Pluschke G. The genome, evolution and diversity of Mycobacterium ulcerans. Infect Genet Evol. 2012;12(3):522-529. DOI: 10.1016/j.meegid.2012.01.018
Röltgen K. Development and application of new approaches to study the epidemiology of Mycobacterium ulcerans disease (Buruli ulcer) in Ghana. Basel: Univ. Basel, 2012. Doctoral Thesis, University of Basel, Faculty of Science DOI: 10.5451/unibas-006055056
Thesis
Scherr N, Röltgen K, Witschel M, Pluschke G. Screening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of Croconazole against Mycobacterium ulcerans. Antimicrob Agents Chemother. 2012;56(12):6410-6413. DOI: 10.1128/AAC.01383-12
Yeboah-Manu D, Röltgen K, Opare W, Asan-Ampah K, Quenin-Fosu K, Asante-Poku A, Ampadu E, Fyfe J, Koram K, Ahorlu C, Pluschke G. Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans. PLoS Negl Trop Dis. 2012;6(1):e1460. DOI: 10.1371/journal.pntd.0001460
Röltgen K, Pluschke G. SNP-Typisierung des Buruli-Ulkus-Erregers. Biospektrum. 2011;17(1):48-51. DOI: 10.1007/s12268-011-0010-x
Journal Article
Röltgen K, Qi W, Ruf M.T, Mensah-Quainoo E, Pidot S.J, Seemann T, Stinear T.P, Käser M, Yeboah-Manu D, Pluschke G. Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of Buruli ulcer in a highly endemic region of Ghana. PLoS Negl Trop Dis. 2010;4(7):e751. DOI: 10.1371/journal.pntd.0000751
Qi W, Käser M, Röltgen K, Yeboah-Manu D, Pluschke G. Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS Pathog. 2009;5(9):1-14
Journal Article