Assessing whether universal coverage with insecticide-treated nets has been achieved: is the right indicator being used? (Publications)
BACKGROUND/METHODS: Insecticide-treated nets (ITNs) are the primary tool for malaria vector control in sub-Saharan Africa, and have been responsible for an estimated two-thirds of the reduction in the
Identifying key bird species and geographical hotspots of avian influenza A (H7N9) virus in China (Publications)
BACKGROUND: In China since the first human infection of avian influenza A (H7N9) virus was identified in 2013, it has caused serious public health concerns due to its wide spread and high mortality ra
Community-based prevalence of typhoid fever, typhus, brucellosis and malaria among symptomatic individuals in Afar Region, Ethiopia (Publications)
BACKGROUND: In sub-Saharan Africa, where there is the scarcity of proper diagnostic tools, febrile illness related symptoms are often misdiagnosed as malaria. Information on causative agents of febril
Detection and monitoring of insecticide resistance mutations in <em>Anopheles gambiae</em>: individual vs pooled specimens (Publications)
Bioassays and molecular diagnostics are routinely used for the monitoring of malaria vector populations to support insecticide resistance management (IRM), guiding operational decisions on which insec
Intestinal parasite infections and associated risk factors among schoolchildren in Dolakha and Ramechhap districts, Nepal: a cross-sectional study (Publications)
BACKGROUND: Infections with soil-transmitted helminths and pathogenic intestinal protozoa pose a considerable public health burden, particularly in low- and middle-income countries, including Nepal. W
Diagnostic accuracy of the InBios Scrub Typhus DetectTM ELISA for the detection of IgM antibodies in Chittagong, Bangladesh (Publications)
Here we estimated the accuracy of the InBios Scrub Typhus Detect immunoglobulin M (IgM) ELISA to determine the optimal optical density (OD) cut-off values for the diagnosis of scrub typhus. Patients w
A rapid appraisal of factors influencing praziquantel treatment compliance in two communities endemic for schistosomiasis in Côte d'Ivoire (Publications)
Over the past decade, a significant reduction in the prevalence of schistosomiasis has been achieved, partially explained by the large-scale administration of praziquantel. Yet, the burden of schistos
Outer membrane protein a conservation among <em>Orientia tsutsugamushi</em> isolates suggests its potential as a protective antigen and diagnostic... (Publications)
Scrub typhus threatens one billion people in the Asia-Pacific area and cases have emerged outside this region. It is caused by infection with any of the multitude of strains of the bacterium Orientia
Sensitivity of the point-of-care circulating cathodic antigen urine cassette test for diagnosis of <em>Schistosoma mansoni</em> in low-endemicity... (Publications)
The sensitivity of a point-of-care circulating cathodic antigen (POC-CCA) urine cassette test for diagnosis of Schistosoma mansoni in low-endemicity settings is poorly understood. We conducted a cross
Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in... (Publications)
BACKGROUND: The RTS,S/AS01E vaccine provides partial protection against malaria in African children, but immune responses have only been partially characterized and do not reliably predict protective