Environmental and health data needed to develop national surveillance systems in industrially contaminated sites (Publications)
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Public health surveillance (PHS) of industrially contaminated sites (ICSs) is likely to play a role in supporting the monitoring of
Integrating standardized whole genome sequence analysis with a global <em>Mycobacterium tuberculosis</em> antibiotic resistance knowledgebase (Publications)
Drug-resistant tuberculosis poses a persistent public health threat. The ReSeqTB platform is a collaborative, curated knowledgebase, designed to standardize and aggregate global Mycobacterium tubercul
<em>In vitro</em> and<em> in vivo</em> drug-drug interaction study of the effects of ivermectin and oxantel pamoate on tribendimidine (Publications)
Soil-transmitted helminth (STH) infections still remain a major health problem in poor rural settings. The lack of efficacious drugs against all STH species raises the interest in drug combinations. D
A review of exposure assessment methods for epidemiological studies of health effects related to industrially contaminated sites (Publications)
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Health risks related to living close to industrially contaminated sites (ICSs) are a public concern. Toxicology-based risk assessmen
Challenges and lessons from conducting a paediatric clinical trial in sub-Saharan Africa: the case of the praziquantel oral dispersible tablets phase... (Publications)
The importance of implementing paediatric clinical trials for neglected tropical diseases (NTDs) in compliance with the Good Clinical Practices of the International Conference of Harmonisation (ICH-GC
Community and drug distributor perceptions and experiences of mass drug administration for the elimination of lymphatic filariasis: a rapid review of... (Publications)
STUDY OBJECTIVES: This article presents findings from a rapid review of qualitative research conducted to inform decision makers about community and drug distributor perceptions and experiences of mas
Antiplasmodial imidazopyridazines: structure-activity relationship studies lead to the identification of analogues with improved solubility and hERG... (Publications)
3,6-Diarylated imidazopyridazines have recently been shown to possess good in vitro antiplasmodial and in vivo antimalarial activity. However, frontrunner compounds have been associated with poor solu
Cell penetration, herbicidal activity, and <em>in-vivo</em>-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived... (Publications)
Oligo-arginines are thoroughly studied cell-penetrating peptides (CPPs, Figures 1 and 2). Previous in-vitro investigations with the octaarginine salt of the phosphonate fosmidomycin (herbicide and ant