Selective anti-leishmanial strathclyde minor groove binders using an N-oxide tail-group modification (Publications)
The neglected tropical disease leishmaniasis, caused by Leishmania spp., is becoming more problematic due to the emergence of drug-resistant strains. Therefore, new drugs to treat leishmaniasis, with
Relatives from hereditary breast and ovarian cancer and lynch syndrome families forgoing genetic testing: findings from the Swiss CASCADE cohort (Publications)
Cascade genetic testing of relatives from families with pathogenic variants associated with hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) has important implications for cancer pre
Implementation approaches for leprosy prevention with single-dose rifampicin: a support tool for decision making (Publications)
BACKGROUND: In the past 15 years, the decline in annually detected leprosy patients has stagnated. To reduce the transmission of Mycobacterium leprae, the World Health Organization recommends single-d
Population genetics of bovine and human schistosomes in Côte d'Ivoire (Publications)
Neglected tropical diseases (NTDs) are a diverse group of infectious disease that severely affect the health of over one billion people in 149 countries across the globe. Schistosomiasis and fasciolia
Pesticide exposure and cortical brain activation among farmworkers in Costa Rica (Publications)
BACKGROUND: Previous epidemiological studies have reported associations of pesticide exposure with poor cognitive function and behavioral problems. However, these findings have relied primarily on neu
Community-based wound management in a rural setting of Côte d'Ivoire (Publications)
BACKGROUND: Wounds are a neglected health problem in rural communities of low-income countries, mostly caused by trauma and ulcerative skin diseases including Neglected Tropical Diseases (NTDs) and as
Skin wounds in a rural setting of Côte d'Ivoire: population-based assessment of the burden and clinical epidemiology (Publications)
BACKGROUND: Data on the burden and clinical epidemiology of skin wounds in rural sub-Saharan Africa is scant. The scale of the problem including preventable progression to chronic wounds, disability a
Air pollution exposure assessment in sparsely monitored settings; applying machine-learning methods with remote sensing data in South Africa (Publications)
Air pollution is one of the leading environmental risk factors to human health – Both short and long-term exposure to air pollution impact human health accounting for over 4 million deaths. Although t
Thermal proteome profiling reveals <em>Haemonchus </em>orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868 (Publications)
Parasitic roundworms (nematodes) cause destructive diseases, and immense suffering in humans and other animals around the world. The control of these parasites relies heavily on anthelmintic therapy,
What the policy and stewardship landscape of a national health research system looks like in a developing country like Iran: a qualitative study (Publications)
BACKGROUND: The health research system (HRS) is an important national priority that requires a systematic and functional approach. Evaluating the HRS of Iran as a developing country and identifying it