Molecular characterization of canine rabies virus, Mali, 2006-2013 (Publications)
We genetically characterized 32 canine rabies viruses isolated in Mali during 2006-2013 and identified 3 subgroups that belonged to the Africa 2 lineage. We also detected subgroup F rabies virus. This
Comparison of the diagnostic accuracy of three rapid tests for the serodiagnosis of hepatic cystic echinococcosis in humans (Publications)
BACKGROUND: The diagnosis of cystic echinococcosis (CE) is based primarily on imaging, in particular with ultrasound for abdominal CE, complemented by serology when imaging results are unclear. In rur
A case series of acquired drug resistance-associated mutations in human immunodeficiency virus-infected children: an emerging public health concern in... (Publications)
The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall succe
Combating poor‑quality anti‑malarial medicines: a call to action (Publications)
The circulation of poor-quality medicines continues to undermine the fight against many life-threatening diseases. Anti-malarial medicines appear to have been particularly compromised and present a ma
Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy (Publications)
The antiplasmodial activity, DMPK properties, and efficacy of a series of quinoline-4-carboxamides are described. This series was identified from a phenotypic screen against the blood stage of Plasmod
Validation of a rapid rabies diagnostic tool for field surveillance in developing countries (Publications)
BACKGROUND: One root cause of the neglect of rabies is the lack of adequate diagnostic tests in the context of low income countries. A rapid, performance friendly and low cost method to detect rabies
Is zidovudine first line therapy virologically comparable to tenofovir in resource-limited settings? (Publications)
OBJECTIVE: To compare virologic success between adult patients on tenofovir (TDF) and zidovudine (AZT)-containing first-line anti-retroviral (ART) regimens in 10 rural clinics in Lesotho, Southern Afr