Helminth and intestinal protozoa infections, multiparasitism and risk factors in Champasack Province, Lao People's Democratic Republic (Publications)
BACKGROUND: Detailed investigations of multiparasitism are scarce in the Mekong River basin. We assessed helminth (trematode, nematode, and cestode), and intestinal protozoa infections, and multiparas
Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy: paradoxical reaction or evidence for immune protection? (Publications)
BACKGROUND: The neglected tropical disease Buruli ulcer (BU) caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic ulcerative skin lesions. Histopathological f
Rosetting in <em>Plasmodium vivax</em>: a cytoadhesion phenotype associated with anaemia (Publications)
BACKGROUND: Plasmodium vivax can potentially lead to life-threatening episodes but the mechanisms underlying severe disease remain poorly defined. Cytoadhesion of infected erythrocytes may contribute
"Communicate to vaccinate": the development of a taxonomy of communication interventions to improve routine childhood vaccination (Publications)
BACKGROUND: Vaccination is a cost-effective public health measure and is central to the Millennium Development Goal of reducing child mortality. However, childhood vaccination coverage remains sub-opt
Fexinidazole: a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness (Publications)
BACKGROUND: Human African trypanosomiasis (HAT), also known as sleeping sickness, is a fatal parasitic disease caused by trypanosomes. Current treatment options for HAT are scarce, toxic, no longer ef
Major surface glycoproteins of insect forms of <em>Trypanosoma brucei</em> are not essential for cyclical transmission by tsetse (Publications)
Procyclic forms of Trypanosoma brucei reside in the midgut of tsetse flies where they are covered by several million copies of glycosylphosphatidylinositol-anchored proteins known as procyclins. It ha