Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of <em>Plasmodium falciparum</em> dUTP... (Publications)
The ubiquitous enzyme dUTP nucleotidohydrolase (dUTPase) catalyses the hydrolysis of dUTP to dUMP and can be considered as the first line of defence against incorporation of uracil into DNA. Inhibitio
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer (Publications)
The purpose of our study was to demonstrate that distinct cytogenetic alterations in the most common subtype of renal cell cancer, clear cell renal cell carcinoma (ccRCC), are reflected in protein exp
Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-<em>O</em>-Methlylamidoxime (Pafuramidine, DB289) against <em>Trypanosoma... (Publications)
Owing to the lack of oral drugs for human African trypanosomiasis, patients have to be hospitalized for 10 to 30 days to facilitate treatment with parenterally administered medicines. The efficacy of
Urban agricultural land use and characterization of mosquito larval habitats in a medium-sized town of Côte d'Ivoire (Publications)
Urban agriculture is common across Africa and contributes to the livelihoods of urban dwellers. Some crop systems create suitable mosquito breeding sites and thus might affect malaria transmission. Th
Introducing insecticide-treated nets in the Kilombero Valley, Tanzania: the relevance of local knowledge and practice for an information, education... (Publications)
Since 1997 the WHO has been recommending an integrative strategy to combat malaria including new medicines, vaccines, improvements of health care systems and insecticide-treated nets (ITNs). After suc
Respiratory symptoms, atopy and bronchial hyperreactivity in professional firefighters (Publications)
The aim of the present study was to assess respiratory health in professional firefighters. A total of 101 male professional firefighters from Basel, Switzerland, were included in the study. A control
Comparative field evaluation of the Mbita trap, the Centers for Disease Control light trap, and the human landing catch for sampling of malaria... (Publications)
The mosquito sampling efficiency of a new bed net trap (the Mbita trap) was compared with that of the Centers for Disease Control miniature light trap (hung adjacent to an occupied bed net) and the hu
Whose logic? The local redistribution of food aid targeting old and chronically sick people in Zambia (Publications)
In 2002-2003, the agro-pastoralist groups in the Kafue Flats of the Southern Province of Zambia were severely affected by famine. Livelihood changes due to an economic crisis decreased the ability of