Safety and immunogenicity profile of an experimental hepatitis B vaccine adjuvanted with AS04 (Publications)
The reactogenicity and safety of an experimental hepatitis B (HB) vaccine containing adjuvant system (AS04) was compared with a licensed vaccine in a phase III, single-blind, randomised study in healt
A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites (Publications)
HPLC based activity profiling is an effective strategy to accelerate the discovery of new hits and leads from nature. It conveniently combines the superior separation power of HPLC micro scale compoun
Immunopeptides in the defense reactions of <em>Glossina morsitans</em> to bacterial and <em>Trypanosoma brucei</em> <em>brucei</em> infections (Publications)
Several dipteran insects are vectors of parasites causing major human infectious diseases. Among these, the tsetse fly, Glossina spp., is responsible for the transmission of trypanosomes, the pathogen
Characterization of a defensin from the sand fly <em>Phlebotomus duboscqi</em> induced by challenge with bacteria or the protozoan parasite... (Publications)
Antimicrobial peptides are major components of the innate immune response of epithelial cells. In insect vectors, these peptides may play a role in the control of gut pathogens. We have analyzed antim