<em>Trypanosoma brucei </em>CTP synthetase: a target for the treatment of African sleeping sickness (Publications)
The drugs in clinical use against African sleeping sickness are toxic, costly, or inefficient. We show that Trypanosoma brucei, which causes this disease, has very low levels of CTP, which are due to
Blood or urine IP-10 cannot discriminate between active tuberculosis and respiratory diseases different from tuberculosis in children (Publications)
OBJECTIVES: Interferon-? inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuberculosis (TB) biomarker for adults. This study aims to evaluate the potential of IP-10 di
Synthesis and antiprotozoal activities of new 3-azabicyclo[3.2.2]nonanes (Publications)
Some antimalarial agents in use typically bear basic side chains as ligands. Such ligands were attached to the amino substituent of a bridgehead atom of already antiprotozoal active 3-azabicyclo[3.2.2