Quinolone amides as anti-trypanosomal lead compounds with in vivo activity (Publications)
Human African Trypanosomiasis (HAT) is a major tropical disease with few available drugs for treatment driving the need for novel active compounds. Recently, morpholino-substituted benzyl amides of th
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virologic failure in Rwanda (Publications)
OBJECTIVE: To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in a large cohort of patients receiving first-line tenofovir-based antiretroviral (ART) regimens. METHODS: A
Giant host red blood cell membrane mimicking polymersomes bind parasite proteins and malaria parasites (Publications)
Malaria is an infectious disease that needs to be addressed using innovative approaches to counteract spread of drug resistance and to establish or optimize vaccination strategies. With our approach,
A research agenda to underpin malaria eradication (Publications)
The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert view suggests that, by aggressively scalin
Spatial and temporal dynamics of malaria transmission in rural western Kenya (Publications)
ABSTRACT: BACKGROUND: Understanding the impact of reducing Plasmodium falciparum malaria transmission requires estimates of the relationship between health outcomes and exposure to infectious mosquito
Household costs of illness during different phases of tuberculosis treatment in Central Asia: a patient survey in Tajikistan (Publications)
BACKGROUND: Illness-related costs incurred by patients constitute a severe economic burden for households especially in low-income countries. High household costs of illness lead to impoverishment; th
Medical care of asylum seekers: a descriptive study of the appropriateness of nurse practitioners' care compared to traditional physician-based care... (Publications)
BACKGROUND: Medical care for asylum seekers is a complex and critical issue worldwide. It is influenced by social, political, and economic pressures, as well as premigration conditions, the process of