Cytotoxic T lymphocyte (CTL) low-responsiveness to the <em>Plasmodium falciparum</em> circumsporozoite protein in naturally-exposed endemic... (Publications)
Cytotoxic T lymphocytes (CTL) specific for epitope(s) within the circumsporozoite (CS) protein of malaria sporozoites have been shown to play an important role in protective immunity against malaria,
Antigens released at schizont burst stimulate <em>Plasmodium falciparum</em>-specific CD4+ T cells from non-exposed donors: potential for... (Publications)
In an individual experiencing the first attack of malaria, symptoms of disease can occur at very low parasitemia. T cells and cytokines have been implicated in the etiology of disease symptoms, and ot
Use of modern and traditional products to self-treat symptoms of sexually transmitted infections in South African women (Publications)
The objective of the study is to investigate products used by women self-treating symptoms of reproductive tract infections (RTIs), including sexually transmitted infections (STIs), and their methods
Relationship between humoral response to <em>Plasmodium falciparum</em> merozoite surface antigen-2 and malaria morbidity in a highly endemic area of... (Publications)
The prevalence and concentration of antibodies to merozoite surface antigen-2 (MSA-2) were measured in blood samples collected during a cross-sectional survey. Antibodies were measured by enzyme-linke
Sequence and expression of a gene from <em>Theileria annulata</em> coding for a 70-kilodalton heat-shock protein (Publications)
A library consisting of randomly sheared Theileria annulata genomic DNA fragments in the vector lambda gt11 was screened with a Drosophila DNA segment containing the coding region of the 70-kDa heat-s
Isolation and functional property of mRNAs coding for human interleukin 2 (Publications)
Interleukin 2 (IL 2) is a lymphokine with specific growth promoting properties for activated T cells. The isolation and purification of specific mRNAs coding for this protein is reported. The analysis
Assessment of the humoral and cell-mediated immunity against the <em>Plasmodium falciparum</em> vaccine candidates circumsporozoite protein and SPf66... (Publications)
To assess natural immunity against the circumsporozoite (CS) protein and the synthetic vaccine SPf66, immunologic studies were carried out in a highly endemic malarious area of Papua New Guinea. Antib
Humoral and cell-mediated immunity to the <em>Plasmodium falciparum</em> ring-infected erythrocyte surface antigen in an adult population exposed to... (Publications)
A parasitological and immunological survey was carried out in an area in Papua New Guinea highly endemic for malaria. Two hundred fourteen adult individuals were selected for studies to assess their i