Quantification of viable bacterial load in artificial sputum spiked with <em>Mycobacterium tuberculosis</em> (Publications)
OBJECTIVE: Artificial sputum spiked with Mycobacterium tuberculosis could serve for validation of procedures that determine viable mycobacterial load. DESIGN: Artificial sputum specimens prepared in-h
Explaining patient delay in healthcare seeking and loss to diagnostic follow-up among patients with presumptive tuberculosis in Tanzania: a... (Publications)
BACKGROUND: Delay in healthcare seeking and loss to diagnostic follow-up (LDFU) contribute to substantial increase in tuberculosis (TB) morbidity and mortality. We examined factors, including perceive
Screening strategy for Chagas disease in a non-endemic country (Switzerland): a prospective evaluation (Publications)
The WHO recommends screening of Latin American migrants for Chagas disease to reduce morbidity and mortality and increase the likelihood of eradicating the disease. The objective was to assess the fea
Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study (Publications)
BACKGROUND: Currently, there is limited evidence on the effectiveness of second-line antiretroviral therapy (ART) in sub-Saharan Africa. To address this challenge, outcomes of second-line protease inh
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles (Publications)
Analogues of a novel class of benzimidazoles with an intramolecular hydrogen bonding motif have been synthesized and evaluated in vitro for their antiplasmodium activity against chloroquine-sensitive
Novel minor groove binders cure animal African trypanosomiasis in an<em> in vivo</em> mouse model (Publications)
Animal African trypanosomiasis (AAT) is a significant socioeconomic burden for sub-Saharan Africa because of its huge impact on livestock health. Existing therapies including those based on minor groo