Total synthesis and antitrypanosomal activity of janadolide and simplified analogues (Publications)
Janadolide is a cyclic depsipeptide natural product isolated from the marine cyanobacterium Okeania sp. Herein, we describe the total synthesis of janadolide, along with eight simplified analogues, vi
Health and economic burden of respiratory syncytial virus (RSV) disease and the cost-effectiveness of potential interventions against RSV among... (Publications)
BACKGROUND: Respiratory syncytial virus (RSV) frequently causes acute lower respiratory infection in children under 5, representing a high burden in Gavi-eligible countries (mostly low-income and lowe
Re-annotation of the <em>Theileria parva</em> genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved... (Publications)
BACKGROUND: The apicomplexan parasite Theileria parva causes a livestock disease called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic
A random forest approach to estimate daily particulate matter, nitrogen dioxide, and ozone at fine spatial resolution in Sweden (Publications)
Air pollution is one of the leading causes of mortality worldwide. An accurate assessment of its spatial and temporal distribution is mandatory to conduct epidemiological studies able to estimate long
Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries (Publications)
OBJECTIVE: To determine the magnitude of relationships of early life Ffactors with child development in low/middle-income countries (LMICs). DESIGN: Meta-analyses of standardised mean differences (SMD
An African origin for<em> Mycobacterium bovis</em> (Publications)
Background and objectives: Mycobacterium bovis and Mycobacterium caprae are two of the most important agents of tuberculosis in livestock and the most important causes of zoonotic tuberculosis in huma
Cost of interventions to control schistosomiasis: a systematic review of the literature (Publications)
BACKGROUND: Schistosomiasis, a disease caused by blood flukes of the genus Schistosoma, belongs to the neglected tropical diseases. Left untreated, schistosomiasis can lead to severe health problems a
Mechanochemical formation of racemic praziquantel hemihydrate with improved biopharmaceutical properties (Publications)
Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the p
A factorial cluster-randomised controlled trial combining home-environmental and early child development interventions to improve child health and... (Publications)
BACKGROUND: Exposure to unhealthy environments and inadequate child stimulation are main risk factors that affect children's health and wellbeing in low- and middle-income countries. Interventions tha
PEBRA trial - effect of a peer-educator coordinated preference-based ART service delivery model on viral suppression among adolescents and young... (Publications)
BACKGROUND: Despite tremendous progress in controlling the HIV epidemic in sub-Saharan Africa, HIV-related mortality continues to increase among adolescents and young people living with HIV (AYPLHIV).