Predictors of residual antimalarial drugs in the blood in community surveys in Tanzania (Publications)
BACKGROUND: Understanding pattern of antimalarials use at large scale helps ensuring appropriate use of treatments and preventing the spread of resistant parasites. We estimated the proportion of indi
Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ul
Meta-analysis of exome array data identifies six novel genetic loci for lung function (Publications)
Background: Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. Methods: We carried out met
Transmission of hepatitis B and D viruses in an African rural community (Publications)
According to the World Health Organization (WHO), an estimated 257 million people worldwide are chronically infected with hepatitis B virus (HBV), with approximately 15 million of them being coinfecte
Development and evaluation of a multiplex quantitative real-time polymerase chain reaction for hookworm species in human stool (Publications)
Hookworm disease caused by Necator americanus, Ancylostoma duodenale, and Ancylostoma ceylanicum affects half a billion people worldwide. The prevalence and intensity of infection of individual hookwo
The prevalence of brucellosis and bovine tuberculosis in ruminants in Sidi Kacem Province, Morocco (Publications)
Bovine tuberculosis (BTB) and brucellosis are major endemic zoonoses in ruminants in Morocco that impact on both animal and human health. This study presents an assessment of the epidemiological and s
The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: rationale and design of the database and the collection of... (Publications)
BACKGROUND: The available evidence on the benefits and harms of novel drugs and therapeutic biologics at the time of approval is reported in publicly available documents provided by the US Food and Dr
Effects of vancomycin and ciprofloxacin on the NMRI mouse metabolism (Publications)
The reduction in gut microbiota diversity is associated with a range of human diseases. Overuse of antibiotics has been associated with a diminished gut-microbial diversity in humans, and may promote
3D-QSAR modeling and synthesis of new fusidic acid derivatives as antiplasmodial agents (Publications)
Wide spread Plasmodium falciparum ( P. falciparum) resistance has compromised existing antimalarial therapies to varying degrees. Novel agents, able to circumvent antimalarial drug resistance, are the