A clinical prediction score in addition to WHO criteria for anti-retroviral treatment failure in resource-limited settings: experience from Lesotho (Publications)
OBJECTIVE: To assess the positive predictive value (PPV) of a clinical score for viral failure among patients fulfilling the WHO-criteria for anti-retroviral treatment (ART) failure in rural Lesotho.
The past and future of tuberculosis research (Publications)
Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, di
How many mosquito nets are needed to achieve universal coverage? Recommendations for the quantification and allocation of long-lasting insecticidal... (Publications)
BACKGROUND: Long-lasting insecticidal nets are an effective tool for malaria prevention, and "universal coverage" with such nets is increasingly the goal of national malaria control programmes. Howeve
The influence of host and bacterial genotype on the development of disseminated disease with <em>Mycobacterium tuberculosis</em> (Publications)
The factors that govern the development of tuberculosis disease are incompletely understood. We hypothesized that some strains of Mycobacterium tuberculosis (M. tuberculosis) are more capable of causi
Sterilising effects of pyriproxyfen on <em>Anopheles arabiensis</em> and its potential use in malaria control (Publications)
BACKGROUND: Insecticide resistance poses a major threat to current vector control campaigns. Insecticides with novel modes of action are therefore in high demand. Pyriproxyfen (PPF), a conventional mo