cART prescription trends in a prospective HIV cohort in rural Tanzania from 2007 to 2011 (Publications)
Comprehensive information on combined antiretroviral therapy (cART) regimens in rural Sub-Saharan Africa over time is scarce, particularly on the use of stavudine (d4T) and second-line regimens. Since
Impact of traffic-related air pollution on acute changes in cardiac autonomic modulation during rest and physical activity: a cross-over study (Publications)
People are often exposed to traffic-related air pollution (TRAP) during physical activity (PA), but it is not clear if PA modifies the impact of TRAP on cardiac autonomic modulation. We conducted a pa
Match-making for pasaconazole through systems thinking (Publications)
Currently available drugs for Chagas' disease are limited by toxicity and low efficacy in the chronic stage. Posaconazole, the most advanced new anti-chagasic drug candidate, did not fully confirm its
Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam,... (Publications)
BACKGROUND: Malaria transmission, primarily mediated by Anopheles gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding. New or improve
Structure-activity relationship studies of orally active antimalarial 2,4-diamino-thienopyrimidines (Publications)
Based on the initial optimization of orally active antimalarial 2,4-diamino-thienopyrimidines and with the help of metabolite identification studies, a second generation of derivatives involving chang
Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection (Publications)
SUMMARY The diagnosis of parasitic worm (helminth) infections requires specialized laboratory settings, but most affected individuals reside in locations without access to such facilities. We tested t
System effectiveness of a targeted free mass distribution of long lasting insecticidal nets in Zanzibar, Tanzania (Publications)
BACKGROUND: Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is