SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols (Publications)
Several 4-amino-6,7-diarylbicyclo[2.2.2]octan-2-ols bearing varying substituents on the aromatic rings were synthesized following a manual method for applying the Hansch approach. All new compounds we
Survey on hearing aid use and satisfaction in Switzerland and their determinants (Publications)
The purpose of this study was to investigate the efficiency of the Swiss hearing aid dispensing system, and to determine factors contributing to successful hearing aid provision. A national cross sect
Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age (Publications)
BACKGROUND: Plasmodium falciparum malaria is a pressing global health problem. A previous study of the malaria vaccine RTS,S (which targets the circumsporozoite protein), given with an adjuvant system
Comparison of the Flotac-400 dual technique and the formalin-ether concentration technique for the diagnosis of human intestinal protozoa infection (Publications)
There is a need for accurate diagnosis of intestinal parasite infections in humans, but currently available copromicroscopic techniques have shortcomings, such as low sensitivity. We compared the diag
Single-center outcome analysis of 1,161 patients with St. Jude medical and ATS open pivot mechanical heart valves (Publications)
BACKGROUND AND AIM OF THE STUDY: The clinical performance of mechanical heart valves and valve-related complications are important safety endpoints in patients after heart valve replacement. In this r
beta-Branched acyclic nucleoside analogues as inhibitors of <em>Plasmodium falciparum</em> dUTPase (Publications)
We report a series of beta-branched acyclic tritylated deoxyuridine analogues as inhibitors of Plasmodium falciparum deoxyuridine-5'-triphosphate nucleotidohydrolase (PfdUTPase), an enzyme involved in