3D imaging of undissected optically cleared <em>Anopheles stephensi </em>mosquitoes and midguts infected with <em>Plasmodium</em> parasites (Publications)
Malaria is a life-threatening disease, caused by Apicomplexan parasites of the Plasmodium genus. The Anopheles mosquito is necessary for the sexual replication of these parasites and for their transmi
Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism (Publications)
Hyper-virulent Streptococcus pneumoniae serotype 1 strains are endemic in Sub-Saharan Africa and frequently cause lethal meningitis outbreaks. It remains unknown whether genetic variation in serotype
Core components and impact of nurse-led integrated care models for home-dwelling older people: a systematic review and meta-analysis (Publications)
BACKGROUND: Integrated care models are highly recommended to overcome care fragmentation in the multimorbid older population. Nurses are potentially ideally situated to fulfil the role as care coordin
<em>Strongyloides stercoralis</em> prevalence and diagnostics in Vientiane, Lao People's Democratic Republic (Publications)
BACKGROUND: Despite the high prevalence of strongyloidiasis in the Laotian population, Laotian hospitals still lack diagnostic capacity to appropriately diagnose Strongyloides stercoralis infections.
Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents (Publications)
Malaria and tuberculosis are still among the leading causes of death in low-income countries. The 1,4-naphthoquinone (NQ) scaffold can be found in a variety of anti-infective agents. Herein, we report
Financial costs of the Zanzibar elimination of schistosomiasis transmission project (Publications)
We estimated the financial costs of different interventions against urogenital schistosomiasis, implemented by the Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project, on Pemba and Ung
Asthma in farm children is more determined by genetic polymorphisms and in non-farm children by environmental factors (Publications)
BACKGROUND: The asthma syndrome is influenced by hereditary and environmental factors. With the example of farm exposure, we study whether genetic and environmental factors interact for asthma. METHOD
Tick species from cattle in the Adama Region of Ethiopia and pathogens detected (Publications)
Ticks will diminish productivity among farm animals and transmit zoonotic diseases. We conducted a study to identify tick species infesting slaughter bulls from Adama City and to screen them for tick-
Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents (Publications)
Herein, relationships between the structures of 1-aminoethyl-substituted chromenes and their antimalarial activities were thoroughly investigated. At first, the methyl moiety in the side chain was rem