Pumilanol, an antiprotozoal isoflavanol from Tephrosia pumila47 (Publications)
A novel isoflavan-4-ol (pumilanol), (rel)-3 beta-(2'-hydroxy-4',5'-methylenedioxyphenyl)-6-methoxy-4 alpha,7-dihydroxybenzo-3,4-dihydropyran (1) and two known flavonoids, tephrinone (2) and rotenone (
Variable host-pathogen compatibility in <em>Mycobacterium tuberculosis</em> (Publications)
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide. Studies have reported human pathogens to have geographically structured population genetics, some of which have b
The competitive cost of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Mathematical models predict that the future of the multidrug-resistant tuberculosis epidemic will depend on the fitness cost of drug resistance. We show that in laboratory-derived mutants of Mycobacte
An individual-based model of <em>Plasmodium falciparum</em> malaria transmission on the coast of Kenya (Publications)
Individual-based models provide powerful tools to model complex interactions characterized by individual variability. This paper presents an object-oriented design for individual-based modelling of Pl
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol (Publications)
[reaction: see text] Photooxygenation of the chiral allylic alcohol 4-methyl-3-penten-2-ol (3) in nonpolar solvents and subsequent Lewis acid-catalyzed peroxyacetalization afforded a series of monocyc
Absence of anti-hepatitis B surface antibody after vaccination does not necessarily mean absence of immune response (Publications)
A small number of subjects vaccinated against hepatitis B do not produce anti-hepatitis B surface (HBs) antibody levels detectable by commercial assays. Others lose detectable anti-HBs at some time af
Imported schistosomiasis in Europe: sentinel surveillance data from TropNetEurop (Publications)
BACKGROUND: Schistosomiasis is a major parasitic disease, increasingly imported into temperate climates by immigrants from and travelers to endemic areas. METHOD: To generate valid data on imported in