<em>IL-33</em> polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort (Publications)
BACKGROUND: IL-33 polymorphisms influence the susceptibility to asthma. IL-33 indirectly induces Th2-immune responses via dendritic cell activation, being important for development of atopic diseases.
Standard genotyping overestimates transmission of <em>Mycobacterium tuberculosis</em> among immigrants in a low incidence country (Publications)
Immigrants from high tuberculosis (TB) incidence regions are a risk group for TB in low-incidence countries such as Switzerland. In a previous analysis of a nationwide collection of 520 Mycobacterium
Ultrasonography of gallbladder abnormalities due to schistosomiasis (Publications)
After malaria, schistosomiasis remains the most important tropical parasitic disease in large parts of the world. Schistosomiasis has recently re-emerged in Southern Europe. Intestinal schistosomiasis
Quinolone amides as anti-trypanosomal lead compounds with in vivo activity (Publications)
Human African Trypanosomiasis (HAT) is a major tropical disease with few available drugs for treatment driving the need for novel active compounds. Recently, morpholino-substituted benzyl amides of th
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virologic failure in Rwanda (Publications)
OBJECTIVE: To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in a large cohort of patients receiving first-line tenofovir-based antiretroviral (ART) regimens. METHODS: A
Giant host red blood cell membrane mimicking polymersomes bind parasite proteins and malaria parasites (Publications)
Malaria is an infectious disease that needs to be addressed using innovative approaches to counteract spread of drug resistance and to establish or optimize vaccination strategies. With our approach,
A research agenda to underpin malaria eradication (Publications)
The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert view suggests that, by aggressively scalin
Spatial and temporal dynamics of malaria transmission in rural western Kenya (Publications)
ABSTRACT: BACKGROUND: Understanding the impact of reducing Plasmodium falciparum malaria transmission requires estimates of the relationship between health outcomes and exposure to infectious mosquito