Comparative genomics of the anopheline glutathione s-transferase epsilon cluster (Publications)
Enzymes of the glutathione S-transferase (GST) family play critical roles in detoxification of xenobiotics across many taxa. While GSTs are ubiquitous both in animals and plants, the GST epsilon class
Cardiac alterations in human African trypanosomiasis (<em>T.b. gambiense</em>) with respect to the disease stage and antiparasitic treatment (Publications)
BACKGROUND: In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds
Health services for Buruli ulcer control: lessons from a field study in Ghana (Publications)
BACKGROUND: Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, is a debilitating disease of the skin and underlying tissue. The first phase of a BU prevention and treatment programme (BUPa
Detectability of <em>Plasmodium falciparum</em> clones (Publications)
ABSTRACT: BACKGROUND: In areas of high transmission people often harbour multiple clones of Plasmodium falciparum, but even PCR-based diagnostic methods can only detect a fraction (the detectability,
Achieving high coverage of larval-stage mosquito surveillance: challenges for a community-based mosquito control programme in urban Dar es Salaam,... (Publications)
BACKGROUND: Preventing malaria by controlling mosquitoes in their larval stages requires regular sensitive monitoring of vector populations and intervention coverage. The study assessed the effectiven
Low utilization of health care services following screening for hypertension in Dar es Salaam (Tanzania): a prospective population-based study (Publications)
BACKGROUND: Drug therapy in high-risk individuals has been advocated as an important strategy to reduce cardiovascular disease in low income countries. We determined, in a low-income urban population,
Harmonisation of variables names prior to conducting statistical analyses with multiple datasets: an automated approach (Publications)
ABSTRACT: BACKGROUND: Data requirements by governments, donors and the international community to measure health and development achievements have increased in the last decade. Datasets produced in su
Health and survival of young chlidren in southern Tanzania (Publications)
BACKGROUND: With a view to developing health systems strategies to improve reach to high-risk groups, we present information on health and survival from household and health facility perspectives in f
Improvements in access to malaria treatment in Tanzania following community, retail sector and health facility interventions - a user perspective (Publications)
BACKGROUND: The ACCESS programme aims at understanding and improving access to prompt and effective malaria treatment. Between 2004 and 2008 the programme implemented a social marketing campaign for i
Improvements in access to malaria treatment in Tanzania after switch to artemisinin combination therapy and the introduction of accredited drug... (Publications)
BACKGROUND: To improve access to treatment in the private retail sector a new class of outlets known as Accredited Drug Dispensing Outlets (ADDO) was created in Tanzania. Tanzania changed its first-li