Design of a phase III cluster randomized trial to assess the efficacy and safety of a malaria transmission blocking vaccine (Publications)
Vaccines interrupting Plasmodium falciparum malaria transmission targeting sexual, sporogonic, or mosquito-stage antigens (SSM-VIMT) are currently under development to reduce malaria transmission. An
Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities (Publications)
Several of the enzymes related to the folate cycle are well-known for their role as clinically validated antimalarial targets. Nevertheless for serine hydroxymethyltransferase (SHMT), one of the key e
The WHO ultrasonography protocol for assessing morbidity due to <em>Schistosoma haematobium</em>: acceptance and evolution over 14 years: systematic... (Publications)
In 2000, the World Health Organization (WHO) published an ultrasound field protocol for assessing morbidity due to schistosomiasis. The present study aims to review the acceptance of the WHO protocol
Cost and sensitivity of on-farm versus slaughterhouse surveys for prevalence estimation and substantiating freedom from disease (Publications)
Within the framework of Swiss surveillance for epizootic diseases, dairy cattle are sampled using bulk tank milk while non-dairy cattle are sampled on the farm. The latter method is costly, time-deman
Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant <em>Staphylococcus aureus</em> to Europe (Publications)
Staphylococcus aureus is emerging globally. Treatment of infections is complicated by increasing antibiotic resistance. We collected clinical data and swabs of returnees with skin and soft tissue infe
Particulate matter composition and respiratory health: the PIAMA birth cohort study (Publications)
BACKGROUND:: Ambient particulate matter (PM) exposure is associated with children's respiratory health. Little is known about the importance of different PM constituents. We investigated the effects o
Health & demographic surveillance system profile: the Rufiji Health and Demographic Surveillance System (Rufiji HDSS) (Publications)
The Rufiji Health and Demographic Surveillance System (HDSS) was established in October 1998 to evaluate the impact on burden of disease of health system reforms based on locally generated data, prior