Bottlenecks and the maintenance of minor genotypes during the life cycle of <em>Trypanosoma brucei</em> (Publications)
African trypanosomes are digenetic parasites that undergo part of their developmental cycle in mammals and part in tsetse flies. We established a novel technique to monitor the population dynamics of
Isolation of <em>Trypanosoma brucei gambiense</em> from cured and relapsed sleeping sickness patients and adaptation to laboratory mice (Publications)
BACKGROUND: Sleeping sickness due to Trypanosoma brucei (T.b.) gambiense is still a major public health problem in some central African countries. Historically, relapse rates around 5% have been obser
A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial (Publications)
OBJECTIVES: Peptides delivered on the surface of influenza virosomes have been shown to induce solid humoral immune responses in experimental animals. High titers of peptide-specific antibodies were a
Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan (Publications)
ABSTRACT: BACKGROUND: Intestinal parasitic infections represent a public health problem in Tajikistan, but epidemiological evidence is scarce. The present study aimed at assessing the extent of helmin
European community respiratory health survey II : final report of work package 5 : historic data of ambient air pollution in 37 European cities of... (Publications)
Starting in 2000, the adult population of 29 of the original 41 (mostly) European centres of the former ECRHS I cross-sectional study (1989-92) is being re- investigated in a cohort study. The primary
From strategy development to routine implementation: the cost of Intermittent Preventive Treatment in Infants for malaria control (Publications)
ABSTRACT: BACKGROUND: Achieving the Millennium Development Goals for health requires a massive scaling-up of interventions in Sub Saharan Africa. Intermittent Preventive Treatment in infants (IPTi) is
Creating an "enabling environment" for taking insecticide treated nets to national scale: the Tanzanian experience (Publications)
INTRODUCTION: Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% o
Target product profile choices for intra-domiciliary malaria vector control pesticide products: repel or kill? (Publications)
BACKGROUND: The most common pesticide products for controlling malaria-transmitting mosquitoes combine two distinct modes of action: 1) conventional insecticidal activity which kills mosquitoes expose