Transition bias influences the evolution of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Transition bias, an overabundance of transitions relative to transversions, has been widely reported among studies of the rates and spectra of spontaneous mutations. However, demonstrating the role of
Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections (Publications)
BACKGROUND: Helminthiases are very prevalent worldwide, yet their treatment and control rely on a handful of drugs. Emodepside, a marketed broad-spectrum veterinary anthelminthic with a unique mechani
The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis (Publications)
Radical cure of Plasmodium vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-g
Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis (Publications)
BACKGROUND: Acute schistosomiasis constitutes a rare but serious condition in individuals experiencing their first prepatent Schistosoma infection. To circumvent costly and time-consuming diagnostics,
Diffuse unilateral subacute neuroretinitis caused by <em>Ancylostoma</em> hookworm (Publications)
Diffuse unilateral subacute neuroretinitis is an ocular infectious disease caused by several distinct nematodes. Definite identification of the involved nematodes is rarely achieved. We report on the
<em>Chlamydia pneumoniae</em> in an ex vivo human artery culture model (Publications)
The role of the obligate intracellular pathogen Chlamydia pneumoniae in the development of atherosclerosis could not be completely clarified. Reasons are the highly discrepant results obtained in the