DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes (Publications)
For the most part metazoan genomes are highly methylated and harbor only small regions with low or absent methylation. In contrast, partially methylated domains (PMDs), recently discovered in a variet
Implementing ideal health policy in a fragile health system: the example of expanding the use of malaria rapid diagnostic tests in mainland Tanzania (Publications)
Malaria confirmation before treatment provides an opportunity for improving the quality of malaria case management in endemic regions. However, increased coverage of this strategy is facing many organ
Assessment of factors influencing retention in the Philippine National Rural Physician Deployment Program (Publications)
BACKGROUND: The 'Doctors to the Barrios' (DTTB) Program was launched in 1993 in response to the shortage of doctors in remote communities in the Philippines. While the Program has attracted physicians
The use of mobile phones for demographic surveillance of mobile pastoralists and their animals in Chad: proof of principle (Publications)
BACKGROUND: Demographic information is foundational for the planning and management of social programmes, in particular health services. The existing INDEPTH network surveillance sites are limited to
Uptake of guidelines on prevention of mother-to-child transmission of HIV in rural Tanzania: time for change (Publications)
Guidelines on prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) are inconsistently implemented in low-income countries. Strategies are needed to improve the upta
Antiprotozoal activity of (e)-cinnamic N-acylhydrazone derivatives (Publications)
A series of 14 (E)-cinnamic N-acylhydrazone derivatives, designed through molecular hybridization between the (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2
1,2-substituted 4-(1H)-quinolones: synthesis, antimalarial and antitrypanosomal activities in vitro (Publications)
A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma bruc
Two trypanocidal dipeptides from the roots of <em>Zapoteca portoricensis</em> (Fabaceae) (Publications)
Zapoteca portoricensis (Jacq) HM Hernandez is used with remarkable efficacy in ethnomedicinal management of tonsillitis in the Eastern part of Nigeria. Previous pharmacological studies have validated
Socioeconomic, cultural and behavioural features of prior and anticipated influenza vaccine uptake in urban and rural Pune district, India: a... (Publications)
INTRODUCTION: Ensuring production capacity of efficacious vaccines for pandemic preparedness alone may not be sufficient for effective influenza control. Community willingness to accept the vaccine is