Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic<em> Escherichia coli</em> in women with a... (Publications)
BACKGROUND: Escherichia coli infections are increasing worldwide in community and hospital settings. The E coli O-antigen is a promising vaccine target. We aimed to assess the safety and immunogenicit
Reversion of antibiotic resistance in <em>Mycobacterium tuberculosis</em> by spiroisoxazoline SMARt-420 (Publications)
Antibiotic resistance is one of the biggest threats to human health globally. Alarmingly, multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis have now spread worldwide. Some
Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design (Publications)
The production of natural product compound libraries has been observed in nature for different organisms such as bacteria, fungi and plants; however, little is known about the mechanisms generating su
Combined stool-based multiplex PCR and microscopy for enhanced pathogen detection in patients with persistent diarrhoea and asymptomatic controls from... (Publications)
Infectious diarrhoea ranks among the leading causes of morbidity worldwide. While most acute diarrhoeal episodes are self-limiting, diagnosis and treatment of persistent diarrhoea (=2 weeks) are cumbe
Growth trends of beech and Norway spruce in Switzerland: the role of nitrogen deposition, ozone, mineral nutrition and climate (Publications)
Understanding the effects of nitrogen deposition, ozone and climate on tree growth is important for planning sustainable forest management also in the future. The complex interplay of all these factor
Prevalence of hepatitis B and C infection in persons living with HIV enrolled in care in Rwanda (Publications)
BACKGROUND: Hepatitis B (HBV) and C (HCV) are important causes of morbidity and mortality in people living with human immunodeficiency virus (HIV). The burden of these co-infections in sub-Saharan Afr
Dynamics of freshwater snails and <em>Schistosoma</em> infection prevalence in schoolchildren during the construction and operation of a multipurpose... (Publications)
BACKGROUND: The construction and operation of small multipurpose dams in Africa have a history of altering the transmission of water-based diseases, including schistosomiasis. The current study was de
Mefloquine at the crossroads? Implications for malaria chemoprophylaxis in Europa [Commentary] (Publications)
Since its introduction to the market in 1985, mefloquine has been used for malaria chemoprophylaxis by more than 35 million travellers. In Europe, in 2014, the European Medicines Agency (EMA) issued r