Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration (Publications)
Large-scale administration of anthelminthic drugs currently is the most widely used intervention for controlling morbidity due to schistosomiasis and soil-transmitted helminthiasis. An important issue
Species variation in the fecal metabolome gives insight into differential gastrointestinal function (Publications)
The metabolic composition of fecal extracts provides a window for elucidating the complex metabolic interplay between mammals and their intestinal ecosystems, and these metabolite profiles can yield i
Complete structural assignment of serratol, a cembrane-type diterpene from <em>Boswellia serrata</em>, and evaluation of its antiprotozoal activity (Publications)
From the dichloromethane extract obtained from the gum resin of Boswellia serrata Roxb. (Burseraceae), a well-known medicinal plant resin ("Indian Olibanum"), the cembrane-type diterpene serratol was
Screening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of Croconazole... (Publications)
An Alamar Blue-based growth inhibition assay has been adapted for the thermosensitive and slow growing pathogen Mycobacterium ulcerans (M. ulcerans). The standardized test procedure enables medium-thr
Systems parasitology: effects of <em>Fasciola hepatica</em> on the neurochemical profile in the rat brain (Publications)
We characterize the integrated response of a rat host to the liver fluke Fasciola hepatica using a combination of (1)H nuclear magnetic resonance spectroscopic profiles (liver, kidney, intestine, brai
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones (Publications)
The anti-trypanosomal activity of six sesquiterpene lactones (helenalin, mexicanin I, 11alpha,13-dihydrohelenalin acetate, chamissonolide, ivalin and isoalantolactone) against the African Trypanosoma
Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzania infants: a randomised, placebo-controlled trial (Publications)
BACKGROUND: Clinical malaria and severe anaemia are major causes of paediatric hospital admission and death in many malaria-endemic settings. In the absence of an effective and affordable vaccine, con