Vaccination with the surface proteins MUL_2232 and MUL_3720 of <em>Mycobacterium ulcerans</em> induces antibodies but fails to provide protection... (Publications)
BACKGROUND: Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African
Interferon-gamma is a crucial activator of early host immune defense against <em>Mycobacterium ulcerans</em> infection in mice (Publications)
Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite
Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the REDUCE* trial (*Reduction in the Use of Corticosteroids in... (Publications)
OBJECTIVE: To analyze prospectively the hypothalamic-pituitary-adrenal (HPA) axis and clinical outcome in patients treated with prednisone for exacerbated chronic obstructive pulmonary disease (COPD).
Sleep problems and work injury types: a study of 180 patients in a Swiss emergency department (Publications)
INTRODUCTION: Sleep problems present a risk for work injuries and are a major occupational health concern worldwide. Knowledge about the influence of sleep problems on work injury patterns is limited.
Investigating the association between long-term exposure to air pollution and greenness with mortality from neurological, cardio-metabolic and chronic... (Publications)
Long-term exposure to air pollution has been associated with increased natural-cause mortality, but the evidence on diagnoses-specific mortality outcomes is limited. Few studies have examined the pote
Efficacy of an acid-oxidising solution against <em>Mycobacterium ulcerans</em> (Publications)
For the treatment of chronic wounds, acid-oxidising solutions (AOSs) with broad-spectrum microbicidal activity without disturbing granulation tissue formation, have been developed. We found AOSs to ef
Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study (Publications)
Background Sensitive diagnostics are needed for effective management and surveillance of schistosomiasis so that current transmission interruption goals set by WHO can be achieved. We aimed to screen