Case report: gnathostomiasis acquired in Costa Rica in a returning traveler to the United Kingdom (Publications)
Gnathostomiasis, caused by infection with nematode parasites in the genus Gnathostoma, is endemic in tropical and temperate zones, and is classically associated with East and Southeast Asia and, more
Multi-dose priming regimens of PfSPZ vaccine: safety and efficacy against controlled human malaria infection in Equatoguinean adults (Publications)
Plasmodium falciparum sporozoites (PfSPZ) Vaccine is composed of radiation-attenuated, aseptic, purified cryopreserved PfSPZ. Multiple clinical trials empirically assessing two to six doses have shown
Intestinal perforation due to adult tapeworm of <em>Taenia</em>: a case report and review of the literature (Publications)
Taeniasis is an intestinal helminth infection due to adult tapeworms belonging to the genus Taenia. Taeniasis remains a major burden in low-income countries in Asia. We present a case of intestinal pe
Hookworm infections: reappraising the evidence for a role of neutrophils in light of NETosis (Publications)
In Hookworm infection, neutrophils have long had the image of the villain, being recruited to the site of larval migration because of damage but participating themselves in tissue injury. With recent
Economic evaluation of disease elimination: an extension to the net-benefit framework and application to human African trypanosomiasis (Publications)
The global health community has earmarked a number of diseases for elimination or eradication, and these goals have often been praised on the premise of long-run cost savings. However, decision makers
Optimizing moxidectin dosing for <em>Strongyloides stercoralis</em> infections: insights from pharmacometric modeling (Publications)
Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile
Using observed incidence to calibrate the transmission level of a mathematical model for <em>Plasmodium vivax</em> dynamics including case management... (Publications)
In this work, we present a simple and flexible model for Plasmodium vivax dynamics which can be easily combined with routinely collected data on local and imported case counts to quantify transmission
Risk factors and spatial distribution of <em>Schistosoma mansoni </em>infection among preschool-aged children in Blapleu, Biankouma district, Western... (Publications)
Schistosoma mansoni infection is common among school-age children (SAC) in western Cote d'Ivoire. Little is known on the infection rate of preschool-aged children (PSAC) due to epidemiological data de
The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites (Publications)
Cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) signalling is essential for the proliferation of Plasmodium falciparum malaria blood stage parasites. The mechanisms regulating t
Vaccine hesitancy and its determinants – a way forward? (Publications)
The availability of highly effective SARS-CoV-2 vaccines brought about renewed hope worldwide to overcome the pandemic, becoming an integral part of public health measures. However, vaccine hesitance,