<em>In vitro</em> and<em> in vivo</em> activity of R- and S-praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel... (Publications)
BACKGROUND: Praziquantel (PZQ) is the mainstay of schistosomiasis control and has been successfully used for decades. However, its mechanism of action is not fully understood. While the majority of st
Bifurcatriol, a new antiprotozoal acyclic diterpene from the brown alga <em>Bifurcaria bifurcata</em> (Publications)
Linear diterpenes that are commonly found in brown algae are of high chemotaxonomic and ecological importance. This study reports bifurcatriol (1), a new linear diterpene featuring two stereogenic cen
Childhood hospitalisation and related deaths in Hanoi, Vietnam: a tertiary hospital database analysis from 2007 to 2014 (Publications)
OBJECTIVE: To describe hospital admission and emergency visit rates and potential risk factors of prolonged hospitalisation and death among children in Hanoi. STUDY DESIGN: A retrospective study revie
Preventive chemotherapy in one year reduces by over 80% the number of individuals with soil-transmitted helminthiases causing morbidity: results from... (Publications)
The morbidity due to Ascaris lumbricoides and Trichuris trichiura is caused by infections of moderate and heavy intensity while hookworm infections of all intensities are recognized to cause morbidity
Efficacy of moxidectin versus ivermectin against <em>Strongyloides stercoralis</em> infections: a randomized controlled non-inferiority trial (Publications)
Background: Infections with Strongyloides stercoralis are of considerable public health relevance. Moxidectin, a well-established drug in veterinary medicine under consideration for regulatory submiss
Disease burden due to gastrointestinal infections among people living along the major wastewater system in Hanoi, Vietnam (Publications)
Background: Despite recent improvements of wastewater treatment capacities in urban areas of Hanoi, Vietnam, microbial pollution is still considerable. There is a paucity of burden estimates due to ga
Cost-estimate and proposal for a development impact bond for canine rabies elimination by mass vaccination in Chad (Publications)
Close to 960,000 humans humans die of rabies each year, most of them in Africa and Asia. Clinical rabies can be prevented by post-exposure prophylaxis (PEP). However, PEP is commonly not available or