Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis (Publications)
Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic dermatitis are largely unknown. We conducted a geno
Particulate matter and subclinical atherosclerosis: associations between different particle sizes and sources with carotid intima-media thickness in... (Publications)
BACKGROUND: Subclinical atherosclerosis has been associated with long-term exposure to particulate matter (PM), but the relevance of particle size and sources of exposure remains unclear. OBJECTIVES:
Air pollution, climate and pollen comparisons in urban, rural and alpine regions in Switzerland (Publications)
The aim of this paper is to show spatial differences and correlations in long- term air pollution measurements in the eight SAPALDIA sites (Swiss Study on Air Pollution and Lung Diseases in Adults, SA
Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? (Publications)
BACKGROUND: Alterations in heart rate variability (HRV) are a potential link between exposure to traffic-related air pollution and cardiovascular mortality. OBJECTIVES: We investigated whether long-te
Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction... (Publications)
Background: Both air pollution and genetic variation have been shown to affect lung function. Their interaction has not been studied on a genome-wide scale to date. Objectives: We aimed to identify, i
Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s
Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study (Publications)
BACKGROUND: Impaired renal function is evolving as an independent marker of the risk of cardiovascular morbidity and mortality. Little is known about the prevalence of impaired renal function and its