Anti-trypanosomal activity of Fexinidazole: a new oral nitroimidazole drug candidate for the treatment of sleeping sickness (Publications)
Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis (HAT)) caused by infection with species of the pro
Health system costs of menstrual regulation and care for abortion complications in Bangladesh (Publications)
CONTEXT: Treatment of complications of unsafe abortion can be a significant financial drain on health system resources, particularly in developing countries. In Bangladesh, menstrual regulation is pro
The European Community Respiratory Health Survey II (Publications)
The European Community Respiratory Health Survey (ECRHS) II will determine the incidence of and risk factors for the development of allergic disease, atopy and rapid loss of lung function in middle-ag
A population-based study on the implementation of treatment recommendations for chemotherapy in early breast cancer (Publications)
BACKGROUND: There is considerable heterogeneity in the use of chemotherapy for patients with early breast cancer (BC), despite international recommendations issued from the National Comprehensive Canc
Perceived environmental housing quality and wellbeing of movers (Publications)
STUDY OBJECTIVE: To examine whether changes in environmental housing quality influence the wellbeing of movers taking into account other dimensions of housing quality and sociodemographic factors. DES
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase-2 genes on the metabolism of artemisinin-based... (Publications)
The pharmacogenetics of antimalarials is poorly known, although its application might be critical to optimize treatment. This population pharmacokinetic-pharmacogenetic study aimed at assessing the ef
Synthesis and activity of azaterphenyl diamidines against <em>Trypanosoma brucei rhodesiense</em> and <em>Plasmodium falciparum</em> (Publications)
A series of azaterphenyl diamidines has been synthesized and evaluated for in vitro antiprotozoal activity against both Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.) and