Source apportionment of population representative samples of PM2.5 in three European cities using structural equation modelling (Publications)
Apportionment of urban particulate matter (PM) to sources is central for air quality management and efficient reduction of the substantial public health risks associated with fine particles (PM(2.5)).
<em>Plasmodium falciparum</em> centromeres display a unique epigenetic makeup and cluster prior to and during schizogony (Publications)
Centromeres are essential for the faithful transmission of chromosomes to the next generation, therefore being essential in all eukaryotic organisms. The centromeres of Plasmodium falciparum, the caus
Durchgängiger Strategieprozess als Erfolgsfaktor einer exzellenten Organisation (Publications)
Das Generieren von neuem Wissen zu drängenden Fragen der öffentlichen Gesundheit, deren Umsetzung und Skalierung sind ressourcenintensive Tätigkeiten, die nicht alleine über kompetitive Forschungsgeld
The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes (Publications)
Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide
Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action (Publications)
Leucinostatin A is one of the most potent antiprotozoal compounds ever described, but little was known on structure-activity relationships (SAR). We used Trypanosoma brucei as a protozoal model organi
A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to... (Publications)
BACKGROUND: Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less
Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of... (Publications)
Antimalarials, in particular artemisinin-based combination therapies (ACTs), are critical tools in reducing the global burden of malaria, which is concentrated in sub-Saharan Africa. Performing and re
Variants associated with <em>HHIP</em> expression have sex-differential effects on lung function (Publications)
Background: Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the f