Long-term dominance of <em>Mycobacterium tuberculosis</em> Uganda family in peri-urban Kampala-Uganda is not associated with cavitary disease (Publications)
BACKGROUND: Previous studies have shown that Mycobacterium tuberculosis (MTB) Uganda family, a sub-lineage of the MTB Lineage 4, is the main cause of tuberculosis (TB) in Uganda. Using a well characte
Tuberculosis in antiretroviral treatment programs in lower income countries: availability and use of diagnostics and screening (Publications)
OBJECTIVES: In resource-constrained settings, tuberculosis (TB) is a common opportunistic infection and cause of death in HIV-infected persons. TB may be present at the start of antiretroviral therapy
Do topical repellents divert mosquitoes within a community? Health equity implications of topical repellents as a mosquito bite prevention tool (Publications)
OBJECTIVES: Repellents do not kill mosquitoes - they simply reduce human-vector contact. Thus it is possible that individuals who do not use repellents but dwell close to repellent users experience mo
Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis (Publications)
BACKGROUND: Preventive chemotherapy represents a powerful but short-term control strategy for soil-transmitted helminthiasis. Since humans are often re-infected rapidly, long-term solutions require im
Beyond antimalarial stock-outs: implications of health provider compliance on out-of-pocket expenditure during care-seeking for fever in south east... (Publications)
BACKGROUND: To better understand how stock-outs of the first line antimalarial, Artemisinin-based Combination Therapy (ACT) and other non-compliant health worker behaviour, influence household expendi
Fast<em> in vitro</em> methods to determine the speed of action and the stage-specificity of anti-malarials in <em>Plasmodium falciparum</em> (Publications)
BACKGROUND: Recent whole cell in vitro screening campaigns identified thousands of compounds that are active against asexual blood stages of Plasmodium falciparum at submicromolar concentrations. Thes